Ophiobolin A from Helminthosporium sp.
Ophiobolin A (CAS: 4611-05-6; C25H36O4; MW: 400.55) is a natural product isolated from Helminthosporium sp. This compound is recognised for its role in intracellular calcium signaling pathways and as a cell biology research tool. Ophiobolin A acts as a calcium antagonist and is valuable in studies related to cell signaling and neuroscience, providing researchers with a specific probe for investigating cellular responses.
- IUPAC
- Cochliobolin A
- Synonyms
- Cochliobolin A

Calcium Antagonist Research
Ophiobolin A functions as a calcium antagonist, making it a valuable tool for researchers studying calcium influx and its effects on cellular processes. It can be used to modulate calcium signaling in various experimental models.
Cell Biology Studies
As a compound influencing intracellular calcium, Ophiobolin A is employed in cell biology to investigate cellular functions regulated by calcium ions. Its activity is crucial for understanding cell growth, death, and differentiation.
Neuroscience Research
The compound's effects on cell signaling make it relevant for neuroscience research, particularly in studying neuronal excitability and synaptic transmission where calcium dynamics are critical. It aids in understanding neurodegenerative processes.
Intracellular Calcium Signaling Probe
Ophiobolin A serves as a specific probe for dissecting the complexities of intracellular calcium signaling pathways. Researchers utilise it to map signaling cascades and identify key regulatory mechanisms within cells.
| Molecular weight | 400.55 |
|---|---|
| Empirical formula | C25H36O4 |
| Assay | ≥95% (HPLC) |
| Storage temperature | 2-8°C |

Hazard statements
- H301Toxic if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ophiobolin A used for?
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Ophiobolin A is used as a calcium antagonist in cell biology research, specifically for studying intracellular calcium signaling and its role in cell signaling and neuroscience.
What is the CAS number and formula for Ophiobolin A?
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The CAS number for Ophiobolin A is 4611-05-6, and its empirical formula is C25H36O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ophiobolin A with a purity of ≥95% as determined by HPLC. This product is intended for research purposes and is not represented as USP, BP, EP, or pharmaceutical grade.
How should Ophiobolin A be handled safely?
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Ophiobolin A is a Danger (GHS06) substance, with hazards including H301, H312, and H332. Appropriate personal protective equipment, such as a dust mask (type N95 US), eyeshields, faceshields, and gloves, must be used. Handle in a well-ventilated area and avoid ingestion, skin contact, and inhalation.
Is Ophiobolin A a controlled substance?
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The provided safety data does not indicate that Ophiobolin A is a scheduled or controlled substance.
How is Ophiobolin A packed and shipped?
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Ophiobolin A is shipped as a UN 2811, Class 6.1, Packing Group III hazardous material. It is typically stored at 2-8°C. As a global supplier, Tech Serve Solutions can export this chemical internationally.
How can I request a quote or sample for Ophiobolin A?
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To request a quote or a sample of Ophiobolin A, please contact the Tech Serve Solutions sales team through our website or by phone. Specify the CAS number 4611-05-6 in your request.
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