Ondansetron hydrochloride dihydrate
Ondansetron hydrochloride dihydrate (CAS: 103639-04-9, C18H19N3O · HCl · 2H2O) is a potent selective serotonin 5-HT3 receptor antagonist. With a molecular weight of 365.85 g/mol, this white powder is primarily recognised for its antiemetic properties. It is widely used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, and surgery. Its role extends to research in cell signaling and neuroscience.
- IUPAC
- 1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one hydrochloride,GR 38032F
- Synonyms
- 1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one hydrochloride,GR 38032F
Antiemetic Therapy
Ondansetron hydrochloride dihydrate is a key active pharmaceutical ingredient used in the prevention and treatment of nausea and vomiting. It is particularly effective in managing side effects associated with cancer treatments such as chemotherapy and radiation therapy, as well as post-operative nausea and vomiting.
Neuroscience Research
As a selective 5-HT3 receptor antagonist, this compound serves as a valuable tool in neuroscience research. It aids in studying serotonin pathways, neurotransmission, and their roles in various physiological and pathological processes, including those affecting the central nervous system.
Cell Biology Studies
The compound's specific interaction with serotonin receptors makes it useful in cell biology research. It can be employed to investigate cellular responses mediated by 5-HT3 receptors and explore their involvement in cell signaling pathways.
| Molecular weight | 365.85 |
|---|---|
| Empirical formula | C18H19N3O · HCl · 2H2O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | H2O: >5 mg/mL |
| Storage temperature | −20°C |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ondansetron hydrochloride dihydrate used for?
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Ondansetron hydrochloride dihydrate is used to prevent and treat nausea and vomiting, especially that caused by cancer treatments like chemotherapy and radiation therapy, and after surgery. It is also utilised in neuroscience and cell biology research.
What is the CAS number and formula for Ondansetron hydrochloride dihydrate?
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The CAS number is 103639-04-9 and the empirical formula is C18H19N3O · HCl · 2H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ondansetron hydrochloride dihydrate with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade unless explicitly stated in the product data.
How should Ondansetron hydrochloride dihydrate be handled safely?
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Ondansetron hydrochloride dihydrate is classified as toxic if swallowed (H301) and requires strict safety precautions. Use with adequate ventilation, wear appropriate personal protective equipment including eyeshields, face shields, gloves, and P2 respirator cartridges. Handle as per the Danger signal word and precautionary statements.
How is Ondansetron hydrochloride dihydrate packed and shipped?
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This chemical is typically supplied as a white powder and stored at -20°C. It is packaged and exported by TSS in compliance with international shipping regulations, including UN 2811 classification for toxic solid organic substances.
How can I request a quote or sample for Ondansetron hydrochloride dihydrate?
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To request a quote or sample, please contact our sales team through the website or by phone, providing the product name and CAS number (103639-04-9).
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