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1-Phenylisatin

CAS 723-89-7C14H9NO2Chemical Synthesis

1-Phenylisatin (CAS: 723-89-7), with the molecular formula C14H9NO2 and a molecular weight of 223.23 g/mol, is a valuable chemical intermediate. It serves as a key building block in organic synthesis, particularly for the preparation of various heterocyclic compounds and biologically active molecules. Its applications span the development of pharmaceuticals, including potential antimycobacterial, antipyretic, antiproliferative, and anticonvulsant agents.

IUPAC
1-Phenyl-2,3-indolinedione,NSC 100013
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1-Phenylisatin (C14H9NO2) — chemical structure, CAS 723-89-7; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC13 to C27Chemical SynthesisHeterocyclic Building BlocksIndoles
01 /Applications

Synthesis of Indolin-2,3-dione Schiff Bases

1-Phenylisatin is a precursor for synthesising indolin-2,3-dione Schiff bases. These compounds have demonstrated potential as antimycobacterial agents in research settings.

Development of Antipyretic and Antiproliferative Agents

This compound is utilised as a reactant in the preparation of novel molecules investigated for their antipyretic and antiproliferative properties.

Research into Neuropathic Pain Treatments

1-Phenylisatin serves as a starting material for the synthesis of selective Cannabinoid Receptor 2 agonists, which are being explored for the treatment of neuropathic pain.

Preparation of Anticonvulsant Phenylacetamides

It is employed in synthetic routes leading to phenylacetamide derivatives, which are studied for their potential anticonvulsant activities.

Synthesis of Galanin Receptor Antagonists

1-Phenylisatin is a reactant in the preparation of selective Galanin GAL3 receptor antagonists, compounds of interest in pharmacological research.

02 /Properties
Molecular weight223.23
Empirical formulaC14H9NO2
Assay97%
ApplicationReactant for preparation of:• Indolin-2,3-dione Schiff bases as potential antimycobacterial agents1• Antipyretic agents2• Antiproliferative agents3• Selective Cannabinoid Receptor 2 Agonists for the Treatment of Neuropathic Pain4• Phenylacetamides as anticonvulsant agents5• Selective Galanin GAL3 Receptor Antagonists6
Melting point138-140 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Toxic (GHS06)
Toxic
Danger

Hazard statements

  • H301Toxic if swallowed
  • H311Toxic in contact with skin
  • H331Toxic if inhaled

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P301IF SWALLOWED
  • P311Call a POISON CENTER or doctor
Protective equipmentEyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Water hazard class (WGK, DE)3
Hazard codes (EU)T
Risk statements (R)23/24/25
Safety statements (S)27-28-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
723-89-7
MDL number
MFCD00082681
PubChem substance
24861496
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 1-Phenylisatin used for?

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1-Phenylisatin is used as a reactant for the preparation of various compounds including indolin-2,3-dione Schiff bases with antimycobacterial potential, antipyretic agents, antiproliferative agents, selective Cannabinoid Receptor 2 agonists for neuropathic pain, phenylacetamides with anticonvulsant properties, and selective Galanin GAL3 receptor antagonists.

What are the CAS number and formula for 1-Phenylisatin?

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The CAS number for 1-Phenylisatin is 723-89-7, and its empirical formula is C14H9NO2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 1-Phenylisatin with an assay of 97%. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.

How should 1-Phenylisatin be handled safely?

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1-Phenylisatin is classified as Danger, with hazards including acute toxicity if swallowed, in contact with skin, or if inhaled (H301-H311-H331). Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator cartridge. Ensure adequate ventilation and follow all safety statements (P261-P280-P301 + P310-P311).

Is 1-Phenylisatin controlled or scheduled?

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The provided data does not indicate that 1-Phenylisatin (CAS: 723-89-7) is a controlled or scheduled substance.

How is 1-Phenylisatin packed, shipped, and exported?

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Tech Serve Solutions packs, ships, and exports 1-Phenylisatin according to international regulations for hazardous materials. Specific packaging details can be provided upon request.

How can I request a sample or quote for 1-Phenylisatin?

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To request a sample or a quote for 1-Phenylisatin, please contact our sales team through the website or by phone, providing your details and the product CAS number (723-89-7).

Need 1-Phenylisatin in a specific grade or volume?