(S)-(−)-N,α-Dimethylbenzylamine
(S)-(−)-N,α-Dimethylbenzylamine (CAS: 19131-99-8) is a chiral amine with the linear formula C6H5CH(CH3)NHCH3 and a molecular weight of 135.21 g/mol. This optically active compound is a valuable building block in asymmetric synthesis. It is primarily employed in the preparation of asymmetric organometallic catalysts, which are crucial for stereoselective chemical transformations.
- IUPAC
- (S)-(−)-N-Methyl-1-phenylethylamine
- Synonyms
- (S)-(−)-N-Methyl-1-phenylethylamine(S)-(-)-N-Methyl-alpha-methylbenzylamine(S)-1-(Methylamino)-1-phenyl-ethane
Asymmetric Organometallic Catalysts
This amine serves as a key precursor for synthesizing asymmetric organometallic catalysts. These catalysts are essential for directing stereoselective reactions, such as conjugate additions to enones, enabling the production of enantiomerically enriched compounds.
Chiral Building Block
As a chiral amine, it functions as a versatile building block in organic synthesis. Its defined stereochemistry allows for its incorporation into more complex chiral molecules, facilitating the construction of specific enantiomers.
Chemical Synthesis Intermediate
It acts as an intermediate in various chemical synthesis pathways where a chiral amine moiety is required. Its utility extends to research and development for novel synthetic methodologies.
| Molecular weight | 135.21 |
|---|---|
| Linear formula | C6H5CH(CH3)NHCH3 |
| Assay | 98% |
| Boiling point | 74-76 °C/11 mmHg(lit.) |
| Density | 0.928 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.512(lit.) |
| Optical activity | [α]20/D −73±5°, c = 2 in chloroform |
| Application | Used to make asymmetric organometallic catalysts (e.g., for conjugate additions to enones).1 |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 61 °C / 141.8 °F |
| Transport (UN / ADR) | UN 2619 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 20/21/22-34 |
| Safety statements (S) | 26-36-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-N,α-Dimethylbenzylamine used for?
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(S)-(−)-N,α-Dimethylbenzylamine is used in the preparation of asymmetric organometallic catalysts for stereoselective chemical transformations, particularly conjugate additions to enones. It also serves as a chiral building block in organic synthesis.
What is the CAS number and chemical formula for (S)-(−)-N,α-Dimethylbenzylamine?
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The CAS number is 19131-99-8, and the linear chemical formula is C6H5CH(CH3)NHCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-N,α-Dimethylbenzylamine with a minimum assay of 98%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.
How should (S)-(−)-N,α-Dimethylbenzylamine be handled safely?
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This compound is classified as Danger, with hazards including H302 (Harmful if swallowed), H312 (Harmful in contact with skin), H314 (Causes severe skin burns and eye damage), and H332 (Harmful if inhaled). Appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, is essential. Handle in a well-ventilated area.
Is (S)-(−)-N,α-Dimethylbenzylamine a controlled substance?
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The provided data does not indicate that (S)-(−)-N,α-Dimethylbenzylamine is a controlled substance.
How is (S)-(−)-N,α-Dimethylbenzylamine packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports (S)-(−)-N,α-Dimethylbenzylamine in compliance with all relevant transportation regulations. Specific packaging details are available upon request.
How can I request a quote or sample for (S)-(−)-N,α-Dimethylbenzylamine?
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To request a quote or sample, please contact our sales department through the website or by phone, providing the product name and CAS number (19131-99-8).
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