(S)-(−)-N-(1-Phenylethyl)succinamic acid
(S)-(−)-N-(1-Phenylethyl)succinamic acid (CAS: 21752-34-1) is a chiral organic compound with the linear formula C<sub>6</sub>H<sub>5</sub>CH(CH<sub>3</sub>)NHCOCH<sub>2</sub>CH<sub>2</sub>CO<sub>2</sub>H and a molecular weight of 221.25 g/mol. This carboxylic acid derivative serves as a valuable building block in asymmetric synthesis and chiral resolution processes. Its defined stereochemistry makes it particularly useful for developing enantiomerically pure compounds in various chemical research and development applications.
- IUPAC
- (S)-(−)-N-(α-Methylbenzyl)succinamidic acid
- Synonyms
- (S)-(−)-N-(α-Methylbenzyl)succinamidic acid

Chiral Resolution Agent
Utilised for the separation of racemic mixtures into their constituent enantiomers due to its inherent chirality. This is crucial in the pharmaceutical industry for isolating active drug isomers.
Asymmetric Synthesis Building Block
Serves as a chiral precursor in the synthesis of complex molecules where specific stereochemistry is required. It enables the controlled introduction of chirality into target compounds.
Research and Development
Employed in academic and industrial laboratories for exploring new synthetic routes and developing novel chiral compounds. Its reactive functional groups allow for diverse chemical transformations.
| Molecular weight | 221.25 |
|---|---|
| Linear formula | C6H5CH(CH3)NHCOCH2CH2CO2H |
| Assay | 98% |
| Optical activity | [α]24/D −111°, c = 2 in ethanol |
| Melting point | 100-104 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-N-(1-Phenylethyl)succinamic acid used for?
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(S)-(−)-N-(1-Phenylethyl)succinamic acid is primarily used as a chiral resolving agent for separating enantiomers and as a chiral building block in asymmetric synthesis for creating enantiomerically pure compounds.
What are the CAS number and chemical formula for this compound?
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The CAS number is 21752-34-1, and the linear formula is C<sub>6</sub>H<sub>5</sub>CH(CH<sub>3</sub>)NHCOCH<sub>2</sub>CH<sub>2</sub>CO<sub>2</sub>H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 98%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.
What are the safety and handling precautions for (S)-(−)-N-(1-Phenylethyl)succinamic acid?
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This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Ensure good ventilation. In case of contact with eyes, rinse cautiously with water for several minutes.
How is this chemical shipped and exported?
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Tech Serve Solutions, established in 1998, is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents. We adhere to all international shipping and export regulations for chemical products.
How can I request a sample or a quote?
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To request a sample or a quote for (S)-(−)-N-(1-Phenylethyl)succinamic acid, please contact our sales team through the website or by phone. Details are available in the contact section.
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