(S)-(−)-N-Boc-5-benzyl-2-oxomorpholine
(S)-(−)-N-Boc-5-benzyl-2-oxomorpholine (CAS: 130317-10-1), with the molecular formula C16H21NO4 and a molecular weight of 291.34 g/mol, is a chiral heterocyclic building block. This compound is primarily utilised in asymmetric synthesis and chemical research. Its specific stereochemistry makes it valuable for constructing complex chiral molecules, finding application in the development of novel pharmaceuticals and advanced materials.
- IUPAC
- tert-Butyl (S)-(−)-5-benzyl-2-oxo-4-morpholinecarboxylate
- Synonyms
- tert-Butyl (S)-(−)-5-benzyl-2-oxo-4-morpholinecarboxylate

Chiral Building Block in Asymmetric Synthesis
This enantiomerically pure morpholine derivative serves as a crucial starting material or intermediate in asymmetric synthesis. It enables the stereoselective construction of complex organic molecules, particularly in pharmaceutical research and development.
Heterocyclic Chemistry Research
As a functionalised morpholine, it is employed in academic and industrial research settings to explore novel heterocyclic compounds and their potential applications in medicinal chemistry and materials science.
Pharmaceutical Intermediate Development
The chiral nature of (S)-(−)-N-Boc-5-benzyl-2-oxomorpholine makes it a valuable intermediate for synthesising stereochemically defined active pharmaceutical ingredients (APIs).
| Molecular weight | 291.34 |
|---|---|
| Empirical formula | C16H21NO4 |
| Assay | 99% |
| Optical activity | [α]20/D −14.5°, c = 2.45 in chloroform |
| Melting point | 98-100 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-N-Boc-5-benzyl-2-oxomorpholine used for?
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(S)-(−)-N-Boc-5-benzyl-2-oxomorpholine is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in chemical and pharmaceutical research.
What are the CAS number and formula for (S)-(−)-N-Boc-5-benzyl-2-oxomorpholine?
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The CAS number is 130317-10-1 and the empirical formula is C16H21NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-N-Boc-5-benzyl-2-oxomorpholine with an assay of 99%. This product is intended for research and laboratory use. TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
What are the safety considerations when handling this compound?
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This compound is classified as a Warning. It can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used. Ensure adequate ventilation.
How is this chemical typically shipped or exported?
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Tech Serve Solutions exports and ships this chemical globally, adhering to all relevant regulations for chemical transport. Packaging details can be provided upon request.
How can I request a sample or obtain a quote?
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To request a sample or obtain a quote for (S)-(−)-N-Boc-5-benzyl-2-oxomorpholine, please contact our sales team through the website or by phone.
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