(S)-(−)-N-(1-Phenylethyl)phthalamic acid
(S)-(−)-N-(1-Phenylethyl)phthalamic acid (CAS: 21752-36-3) is a chiral organic compound with a molecular weight of 269.30 g/mol. This carboxylic acid derivative serves as a valuable chiral building block in asymmetric synthesis. Its specific stereochemistry makes it useful in the preparation of enantiomerically pure compounds and as a chiral resolving agent for separating racemic mixtures. It is widely employed in chemical synthesis research and development.
- IUPAC
- (S)-(−)-N-(α-Methylbenzyl)phthalamic acid,(S)-(−)-N-(α-Methylbenzyl)phthalic acid monoamide
- Synonyms
- (S)-(−)-N-(α-Methylbenzyl)phthalamic acid(S)-(−)-N-(α-Methylbenzyl)phthalic acid monoamide
![(S)-(−)-N-(1-Phenylethyl)phthalamic acid (2-[C6H5CH(CH3)NHCO]C6H4CO2H) — chemical structure, CAS 21752-36-3; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F21752-36-3.png&w=3840&q=75)
Chiral Building Block
Utilized as a fundamental component in the synthesis of complex chiral molecules, enabling the construction of specific stereoisomers essential for pharmaceuticals and fine chemicals.
Chiral Resolution Reagent
Employed to separate racemic mixtures into their individual enantiomers, a critical process in producing optically pure compounds for various chemical and biological applications.
Asymmetric Synthesis
Serves as a key intermediate or auxiliary in asymmetric reactions, facilitating the creation of products with high enantiomeric excess.
Organic Synthesis Intermediate
A versatile reactant in multi-step organic synthesis pathways, contributing specific structural features and chirality to target molecules.
| Molecular weight | 269.30 |
|---|---|
| Linear formula | 2-[C6H5CH(CH3)NHCO]C6H4CO2H |
| Assay | 97% |
| Optical activity | [α]24/D −46°, c = 2 in ethanol |
| Melting point | 130-135 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-N-(1-Phenylethyl)phthalamic acid used for?
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(S)-(−)-N-(1-Phenylethyl)phthalamic acid is primarily used as a chiral building block in asymmetric synthesis and as a chiral resolution reagent for separating racemic mixtures into enantiomers.
What is the CAS number and formula for (S)-(−)-N-(1-Phenylethyl)phthalamic acid?
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The CAS number is 21752-36-3, and its linear formula is 2-[C<sub>6</sub>H<sub>5</sub>CH(CH<sub>3</sub>)NHCO]C<sub>6</sub>H<sub>4</sub>CO<sub>2</sub>H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-N-(1-Phenylethyl)phthalamic acid with an assay of 97%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.
What are the safety considerations for handling this chemical?
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This compound is classified with GHS07 symbol and carries a Warning signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is this chemical packed and shipped?
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Tech Serve Solutions, as a specialist global supplier and exporter, packs and ships chemicals according to international safety and transport regulations, ensuring product integrity and safe delivery worldwide.
How can I request a sample or quote for (S)-(−)-N-(1-Phenylethyl)phthalamic acid?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing your details and the product information, including the CAS number 21752-36-3.
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