1,1′-Oxalyldiimidazole
1,1′-Oxalyldiimidazole (CAS: 18637-83-7) is a valuable organic compound with the molecular formula C8H6N4O2 and a molecular weight of 190.16 g/mol. This technical grade reagent serves as an effective coupling agent in organic synthesis. It is particularly useful in the formation of amide and ester bonds, finding applications in peptide chemistry and the synthesis of complex molecules. Tech Serve Solutions supplies this compound for research and development purposes.
- IUPAC
- Oxalic acid diimidazolide
- Synonyms
- Oxalic acid diimidazolide1,1'-Carbonyldiimidazole, N-oxalyl derivative
Amide Bond Formation
1,1′-Oxalyldiimidazole acts as an efficient reagent for the synthesis of amides from carboxylic acids and amines. This reaction is fundamental in constructing peptide chains and other biologically relevant molecules.
Ester Synthesis
This compound facilitates the esterification of carboxylic acids with alcohols. It provides a reliable method for forming ester linkages, which are common in pharmaceuticals and natural products.
Peptide Coupling
As a derivative of carbonyldiimidazole, it is employed in peptide coupling reactions, enabling the efficient linkage of amino acids for the synthesis of peptides and peptidomimetics.
Organic Synthesis Reagent
Its reactivity makes it a versatile tool in general organic synthesis for the activation of carboxylic acids and subsequent nucleophilic substitution reactions.
| Molecular weight | 190.16 |
|---|---|
| Empirical formula | C8H6N4O2 |
| Grade | technical grade |
| Melting point | 114-116 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3259 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 21/22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,1′-Oxalyldiimidazole used for?
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1,1′-Oxalyldiimidazole is primarily used as a coupling agent in organic synthesis, particularly for the formation of amide and ester bonds, including in peptide chemistry.
What is the CAS number and molecular formula for 1,1′-Oxalyldiimidazole?
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The CAS number is 18637-83-7 and the molecular formula is C8H6N4O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,1′-Oxalyldiimidazole as a technical grade product. We do not represent this product as USP, BP, or EP grade.
How should 1,1′-Oxalyldiimidazole be handled safely?
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1,1′-Oxalyldiimidazole is a Danger hazard (H302, H312, H314), causing harm if swallowed or in contact with skin, and severe skin burns and eye damage. Always use appropriate personal protective equipment including eyeshields, face shields, gloves, and respiratory protection (type N100 US / P3 EN143). Handle in a well-ventilated area and follow safety statements P280, P305 + P351 + P338, and P310.
How is 1,1′-Oxalyldiimidazole packed and shipped?
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1,1′-Oxalyldiimidazole is shipped as UN 3259, Class 8, Packing Group III. We ensure compliant packaging for domestic and international export.
How can I request a sample or quote for 1,1′-Oxalyldiimidazole?
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To request a sample or a quotation for 1,1′-Oxalyldiimidazole, please contact our sales team through our website or by phone.
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