NH125

CAS 278603-08-0C27H45IN2Biochemicals & Reagents

NH125 (CAS: 278603-08-0), with the molecular formula C27H45IN2 and a molecular weight of 524.56 g/mol, is a white to off-white solid. This compound functions as an inhibitor, specifically targeting Eukaryotic Elongation Factor-2 Kinase (eEF-2K). It is commonly employed in biochemical research and cell biology studies, particularly within the realms of cell signaling and neuroscience, to investigate cellular processes regulated by protein synthesis and kinase activity.

IUPAC: 1-Benzyl-3-cetyl-2-methylimidazolium iodide

Email us

NH125 (C27H45IN2) — chemical structure, CAS 278603-08-0; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBiochemicals and ReagentsCell BiologyD to KElongation factor-2 KinaseEnzyme InhibitorsEnzyme Inhibitors by EnzymeEnzymesInhibitorsand Substrates

01 /Applications

Eukaryotic Elongation Factor-2 Kinase (eEF-2K) Inhibition

NH125 serves as a potent inhibitor of Eukaryotic Elongation Factor-2 Kinase (eEF-2K). This activity makes it a valuable tool for researchers studying the regulation of protein synthesis and cellular responses to stress or signaling pathways involving eEF-2K.

Cell Signaling Research

As a modulator of eEF-2K, NH125 can be utilised in studies investigating complex cell signaling cascades. Its application aids in understanding how kinase activity influences downstream cellular events, including those related to neuroscience.

Biochemical and Cell Biology Studies

The compound is applicable in broader biochemical and cell biology research. Its defined inhibitory action allows for precise experimental design in investigating cellular mechanisms and the role of specific kinases.

02 /Properties

Molecular weight	524.56
Empirical formula	C27H45IN2
Assay	≥98% (HPLC)
Form	solid
Colour	white to off-white
Solubility	DMSO: >20 mg/mL
Storage temperature	−20°C
Melting point	88.2-94.9 °C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

278603-08-0

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is NH125 used for?

NH125 is primarily used as an inhibitor of Eukaryotic Elongation Factor-2 Kinase (eEF-2K) in biochemical and cell biology research, particularly for studies in cell signaling and neuroscience.

What are the CAS number and formula for NH125?

The CAS number for NH125 is 278603-08-0, and its molecular formula is C27H45IN2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies NH125 with a purity of ≥98% (HPLC). This product is intended for research purposes and is not represented as USP, BP, EP, or pharmaceutical grade.

How should NH125 be handled safely?

NH125 is classified with GHS07 symbol and a Warning signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be worn. Handle in a well-ventilated area, avoiding dust formation. Store at −20°C.

How is NH125 shipped and exported?

Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. NH125 is shipped and exported following international regulations for chemical transport. Specific shipping details can be provided upon request.

How can I request a sample or quote for NH125?

To request a sample or a quote for NH125, please contact our sales department through the website or by phone, providing your details and the quantity required.