NIR-628
NIR-628 (CAS: 243670-16-8, Formula: C34H28N2O4) is a specialized near-infrared (NIR) fluorescence dye. It is designed for applications where the inherent fluorescence of biomolecules can interfere with accurate detection. By utilizing NIR fluorescence (650–900 nm), NIR-628 offers enhanced contrast between target and background signals, overcoming natural fluorescence interference in biological assays and imaging.
- IUPAC
- 2,10-Bis(3-aminopropoxy)dibenzo[a,j]perylene-8,16-dione,3,3′-[(8,16-Dihydro-8,16-dioxodibenzo[a,j]perylen-2,10-diyl)dioxy]dipropylamine

High-Contrast Biological Imaging
NIR-628's near-infrared fluorescence minimizes interference from autofluorescent biomolecules. This allows for clearer visualization of target tissues and structures in biological samples.
Fluorescent Assays
This dye is employed in assays where distinguishing between labelled targets and background biological material is critical. Its emission in the NIR spectrum provides a significant advantage over visible fluorophores.
Biomarker Detection
Utilised for detecting biomarkers in complex biological matrices, NIR-628 helps achieve a higher signal-to-noise ratio, improving assay sensitivity and reliability.
| Molecular weight | 528.60 |
|---|---|
| Empirical formula | C34H28N2O4 |
| Assay | ≥98.0% (HPCE) |
| Solubility | acetonitrile: soluble0.5%, clear |
| Application | NIR-628, a near-infrared (NIR) fluorescence dye, is used in applications where the intrinsic fluorescence of biomolecules poses a problem in the assay. Near-infrared (NIR) fluorescence (650–900 nm) detection avoids the natural background fluorescence interference of biomolecules, providing a high contrast between target and background tissues. |
| Suitability | suitable for fluorescence |
| Melting point | 186-190 °C |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 610 nm; λem 658 nm in acetonitrile |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is NIR-628 used for?
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NIR-628 is a near-infrared (NIR) fluorescence dye used in applications where the intrinsic fluorescence of biomolecules can interfere with assays. It helps provide high contrast between target and background by emitting in the 650–900 nm range.
What are the CAS number and formula for NIR-628?
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The CAS number for NIR-628 is 243670-16-8, and its empirical formula is C34H28N2O4.
What grade and purity does Tech Serve Solutions supply for NIR-628?
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Tech Serve Solutions supplies NIR-628 with a minimum purity of ≥98.0% (HPCE). We do not represent this product as USP, BP, or EP grade.
What are the main safety hazards associated with NIR-628?
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NIR-628 is classified with a Warning signal word. It has hazard statements H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H335 (May cause respiratory irritation), and H413 (May cause long lasting harmful effects to aquatic life). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used.
How is NIR-628 typically shipped and exported by TSS?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, ensuring appropriate packaging and documentation for international shipment of NIR-628.
How can I request a quote or sample of NIR-628?
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To request a quote or sample of NIR-628, please contact our sales team through the website or by phone.
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