O-Phospho-L-serine

CAS 407-41-0(HO)2P(O)OCH2CH(NH2)CO2HBiochemicals & Reagents

O-Phospho-L-serine (CAS 407-41-0) is a phosphorylated derivative of the amino acid L-serine, with the linear formula (HO)2P(O)OCH2CH(NH2)CO2H and a molecular weight of 185.07 g/mol. This biochemical compound is recognised for its role in various biological processes, particularly in cell signalling and metabolic pathways. It is commonly utilised in research settings as a reagent for biochemical studies and as a component in cell culture media.

IUPAC: L-2-Amino-3-hydroxypropanoic acid 3-phosphate,L-SOP,L-Serine O-phosphate
Synonyms: L-Serine O-phosphateL-SOPL-2-Amino-3-hydroxypropanoic acid 3-phosphate

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O-Phospho-L-serine ((HO)2P(O)OCH2CH(NH2)CO2H) — chemical structure, CAS 407-41-0; Life Science, fine chemical supplied by Tech Serve Solutions

Amino AcidAmino Acid LibraryBioactive Small MoleculesBiochemicals and ReagentsCell BiologyExcitatory Amino AcidsGPCR ModulatorsGPCR ProteinsModulators and AntibodiesMetabolic Libraries

01 /Applications

Biochemical Research Reagent

O-Phospho-L-serine serves as a valuable reagent in biochemical research, aiding studies into metabolic pathways and cell signalling mechanisms. Its structure as a phosphorylated amino acid makes it useful for investigating enzyme activity and protein modification.

Cell Biology Studies

Utilised in cell biology, this compound can be incorporated into cell culture media to investigate its effects on cellular processes. It is particularly relevant for research into excitatory amino acids and their associated receptors.

GPCR Modulation Research

As a modulator for GPCR proteins, O-Phospho-L-serine is employed in research focused on G protein-coupled receptor signalling pathways. This aids in the understanding of complex cellular communication systems.

02 /Properties

Molecular weight	185.07
Linear formula	(HO)2P(O)OCH2CH(NH2)CO2H
Assay	~95% (TLC)
Solubility	H2O: soluble50 mg/mL, clear, colorless to slightly yellow (hot)
Impurities tested	≤2% water
Melting point	190 °C(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

407-41-0

MDL number

MFCD00065935

Beilstein registry

1726826

05 /Additional specifications

Gene Information	human ... GRM4(2914), GRM7(2917), GRM8(2918)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is O-Phospho-L-serine used for?

O-Phospho-L-serine is primarily used as a biochemical research reagent for studies in cell biology, cell signalling, and metabolic pathways, particularly in relation to GPCR modulation.

What is the CAS number and chemical formula for O-Phospho-L-serine?

The CAS number for O-Phospho-L-serine is 407-41-0. Its linear chemical formula is (HO)2P(O)OCH2CH(NH2)CO2H.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies O-Phospho-L-serine with an assay of approximately 95% as determined by TLC, with no more than 2% water content. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

What are the safety and handling considerations for O-Phospho-L-serine?

Handling O-Phospho-L-serine requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It has a WGK rating of 3 in Germany.