3,4,5-Trifluorocinnamic acid
3,4,5-Trifluorocinnamic acid (CAS: 152152-19-7) is a fluorinated organic building block with a molecular weight of 202.13 g/mol. This compound, primarily supplied in its trans isomeric form with an assay of 97%, serves as a valuable intermediate in chemical synthesis. Its trifluorinated phenyl ring and carboxylic acid functionality make it suitable for various organic transformations, particularly in the development of novel materials and active pharmaceutical ingredients.
- Synonyms
- 152152-19-7CF3C6H2CH=CHCO2H

Organic Synthesis Intermediate
Utilised as a key building block in complex organic synthesis pathways. Its unique trifluorinated structure allows for the introduction of specific properties into target molecules.
Pharmaceutical Research
Serves as a precursor in the development of new pharmaceutical agents. The presence of fluorine atoms can modulate a compound's metabolic stability, lipophilicity, and binding affinity.
Materials Science
Incorporated into the design of novel polymers and functional materials. The fluorinated aromatic system can influence electronic and physical characteristics of the resulting materials.
| Molecular weight | 202.13 |
|---|---|
| Linear formula | CF3C6H2CH=CHCO2H |
| Assay | 97% (predominantly trans) |
| Melting point | 195-199 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4,5-Trifluorocinnamic acid used for?
+
3,4,5-Trifluorocinnamic acid is used as a building block in organic synthesis, particularly for pharmaceutical research and the development of new materials. Its fluorinated structure makes it valuable for modifying molecular properties.
What is the CAS number and chemical formula for 3,4,5-Trifluorocinnamic acid?
+
The CAS number is 152152-19-7. The linear formula is CF3C6H2CH=CHCO2H.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3,4,5-Trifluorocinnamic acid with an assay of 97% (predominantly trans). We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should 3,4,5-Trifluorocinnamic acid be handled safely?
+
3,4,5-Trifluorocinnamic acid is a Warning compound (GHS07) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). When handling, use a dust mask type N95 (US), wear eyeshields and gloves. Ensure adequate ventilation and avoid breathing dust. Refer to the Safety Data Sheet (SDS) for comprehensive handling instructions.
Does Tech Serve Solutions export 3,4,5-Trifluorocinnamic acid?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3,4,5-Trifluorocinnamic acid, serving clients worldwide.
How can I request a sample or quote for 3,4,5-Trifluorocinnamic acid?
+
To request a sample or a quote for 3,4,5-Trifluorocinnamic acid, please contact our sales department through the website or by phone. Our team will be happy to assist you with your inquiry.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis