3,4,5-Trifluorophenylmagnesium bromide solution
3,4,5-Trifluorophenylmagnesium bromide solution (CAS: 156006-28-9) is a trifluorinated aryl Grignard reagent supplied by Tech Serve Solutions. With a molecular weight of 235.28 g/mol, this organometallic compound is provided as a 0.3 M solution in Tetrahydrofuran (THF). Its reactive nature makes it a valuable tool in organic synthesis for introducing the 3,4,5-trifluorophenyl moiety into various molecular structures.
- Synonyms
- 156006-28-9F3C6H2MgBr
Organofluorine Synthesis
Serves as a key building block for incorporating the 3,4,5-trifluorophenyl group into complex organic molecules. This is particularly relevant in the synthesis of pharmaceuticals and agrochemicals where fluorine substitution can modulate biological activity.
Grignard Reagent Chemistry
As a Grignard reagent, it participates in nucleophilic addition reactions with aldehydes, ketones, esters, and other electrophiles. This enables the formation of new carbon-carbon bonds, crucial for constructing target molecules.
Material Science Applications
The trifluorophenyl unit can impart unique electronic and physical properties to materials. This reagent can be used in the synthesis of monomers or polymers for advanced material applications.
| Molecular weight | 235.28 |
|---|---|
| Linear formula | F3C6H2MgBr |
| Boiling point | 65 °C |
| Density | 0.975 g/mL at 25 °C |
| Concentration | 0.3 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37/38-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4,5-Trifluorophenylmagnesium bromide solution used for?
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3,4,5-Trifluorophenylmagnesium bromide solution is primarily used in organic synthesis for introducing the 3,4,5-trifluorophenyl group into target molecules, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials. It functions as a trifluorinated aryl Grignard reagent for carbon-carbon bond formation.
What are the CAS number and formula for this compound?
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The CAS number for 3,4,5-Trifluorophenylmagnesium bromide solution is 156006-28-9. The linear formula is F<sub>3</sub>C<sub>6</sub>H<sub>2</sub>MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,4,5-Trifluorophenylmagnesium bromide solution at a concentration of 0.3 M in THF. We do not represent this product as USP, BP, or EP grade. Customers requiring specific purity should contact us to discuss their needs.
What are the safety and handling precautions for this chemical?
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This product is classified with Danger signal word and is flammable (H225). It causes severe skin burns and eye damage (H314) and may cause respiratory irritation (H335). It is also suspected of causing cancer (H351). It may form explosive peroxides. Handle in a well-ventilated area, away from ignition sources, using appropriate personal protective equipment. Store at 2-8°C. Refer to the Safety Data Sheet for detailed information.
How is this product packed, shipped, and exported?
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This chemical is packed according to regulatory standards for hazardous materials. It is shipped and exported globally by Tech Serve Solutions, complying with all relevant international transportation regulations for dangerous goods, including UN 2924 classification.
How can I request a quote or sample?
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To request a quote or a sample, please visit the Tech Serve Solutions website and navigate to the product page for 3,4,5-Trifluorophenylmagnesium bromide solution. You can use the online inquiry form or contact our sales team directly.
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