Guaiacol
Guaiacol (CAS 90-05-1), with the molecular formula (CH₃O)C₆H₄OH and a molar mass of 124.14 g/mol, is a naturally occurring phenolic compound. It is a key building block in chemical synthesis and finds applications in various research fields, including cell biology and nutrition research. Guaiacol is known for its characteristic aroma and is also identified as a phytochemical present in Curcuma longa (Turmeric).
- IUPAC
- 2-Methoxyphenol,Catechol monomethyl ether,Pyrocatechol monomethyl ether
- Synonyms
- 2-MethoxyphenolCatechol monomethyl etherPyrocatechol monomethyl ether

Chemical Synthesis Intermediate
Guaiacol serves as a valuable intermediate in the synthesis of various organic compounds. Its phenolic and methoxy functionalities allow for diverse chemical transformations, making it useful in constructing more complex molecules.
Research Chemical
This compound is utilised in research laboratories for studies in areas such as cell biology and nutrition. Its natural occurrence and chemical properties make it an interesting subject for biochemical investigations.
Phytochemical Analysis
As a known constituent of plants like Turmeric, Guaiacol is relevant in phytochemical research. It can be used as a standard or reference compound in the analysis of natural product extracts.
| Molecular weight | 124.14 |
|---|---|
| Linear formula | (CH3O)C6H4OH |
| Assay | ≥98.0% (GC) |
| Grade | purum |
| Boiling point | 205 °C(lit.) |
| Density | 1.129 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.543(lit.) |
| Melting point | 26-29 °C(lit.)26-29 °C |
| Vapour pressure | 0.11 mmHg (25 °C) |
| Vapour density | 4.27 (vs air) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Flash point | 82 °C / 179.6 °F |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Guaiacol used for?
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Guaiacol (CAS 90-05-1) is primarily used as a chemical synthesis intermediate and a research chemical in fields like cell biology and nutrition. It is also relevant in phytochemical analysis due to its presence in plants such as Turmeric.
What is the CAS number and molecular formula for Guaiacol?
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The CAS number for Guaiacol is 90-05-1, and its linear molecular formula is (CH₃O)C₆H₄OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Guaiacol at a grade of 'purum' with an assay of ≥98.0% (GC). We do not represent this product as USP, BP, or EP grade.
How should Guaiacol be handled safely?
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Guaiacol is classified with GHS07 symbol and a Warning signal word, carrying hazard statements H302 (Harmful if swallowed), H315 (Causes skin irritation), and H319 (Causes serious eye irritation). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, faceshields, and gloves, should be worn during handling. Ensure adequate ventilation and refer to the full safety data sheet for detailed handling procedures.
How is Guaiacol packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports Guaiacol in compliance with all relevant chemical handling and transportation regulations, ensuring product integrity and safety throughout the supply chain.
How can I request a sample or quote for Guaiacol?
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To request a sample or a quote for Guaiacol, please contact our sales team through the website or by phone, providing your specific requirements and contact details.
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