3,4,5-Trifluorobenzyl alcohol
3,4,5-Trifluorobenzyl alcohol (CAS 220227-37-2) is a fluorinated aromatic alcohol with the molecular formula F3C6H2CH2OH and a molecular weight of 162.11 g/mol. This compound serves as a valuable building block in organic synthesis. Its unique trifluorinated structure makes it useful for introducing fluorinated moieties into more complex molecules, particularly in the development of pharmaceuticals and agrochemicals. It is supplied by Tech Serve Solutions with an assay of 95%.
- Synonyms
- 220227-37-2, F3C6H2CH2OH

Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of complex organic molecules. The trifluorinated benzyl group can be incorporated into diverse molecular scaffolds.
Pharmaceutical Research
A building block for the development of novel pharmaceutical agents. Fluorine substitution can significantly influence a drug candidate's metabolic stability, lipophilicity, and binding affinity.
Agrochemical Development
Employed in the creation of new agrochemical compounds. Fluorinated organic molecules often exhibit enhanced efficacy and altered environmental persistence.
Material Science
Potential applications in material science for the synthesis of fluorinated polymers or speciality materials where its unique properties can be leveraged.
| Molecular weight | 162.11 |
|---|---|
| Linear formula | F3C6H2CH2OH |
| Assay | 95% |
| Boiling point | 203-204 °C/760 mmHg(lit.) |
| Density | 1.385 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4700(lit.) |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4,5-Trifluorobenzyl alcohol used for?
+
3,4,5-Trifluorobenzyl alcohol is primarily used as a building block in organic synthesis, particularly for introducing trifluorinated benzyl groups into target molecules in pharmaceutical and agrochemical research and development.
What are the CAS number and molecular formula for 3,4,5-Trifluorobenzyl alcohol?
+
The CAS number is 220227-37-2 and the linear molecular formula is F3C6H2CH2OH.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3,4,5-Trifluorobenzyl alcohol with an assay of 95%. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations when handling 3,4,5-Trifluorobenzyl alcohol?
+
When handling 3,4,5-Trifluorobenzyl alcohol, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. Respiratory protection, such as a half-mask respirator, is also recommended. The compound has a WGK Germany rating of 3, indicating it is hazardous to water.
How is 3,4,5-Trifluorobenzyl alcohol packed and exported?
+
3,4,5-Trifluorobenzyl alcohol is carefully packaged to ensure safe handling and transit. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a quote or sample for 3,4,5-Trifluorobenzyl alcohol?
+
To request a quote or sample for 3,4,5-Trifluorobenzyl alcohol, please contact our sales team through the website or by phone. We are happy to assist with your chemical sourcing needs.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis