4-Morpholinopiperidine
4-Morpholinopiperidine (CAS: 53617-35-9, C9H16N2O) is a heterocyclic organic compound supplied by TSS. With a molecular weight of 168.24 g/mol, this chemical serves as a valuable building block in organic synthesis. Its structure, incorporating both morpholine and piperidine rings, makes it a versatile intermediate for creating complex molecules with potential applications in pharmaceuticals and materials science.
- IUPAC
- 4-(4-Piperidinyl) morpholine

Pharmaceutical Intermediate
4-Morpholinopiperidine is utilized as a key reactant in the synthesis of various pharmacologically active compounds. It is instrumental in developing selective adenosine A2A receptor antagonists and novel antidepressants.
Drug Discovery Research
This compound is employed in the creation of small molecules designed to restore E-cadherin expression and inhibit invasion in colorectal carcinoma cells. It also aids in the development of orally bioavailable P2Y12 antagonists for antiplatelet therapies.
Antimicrobial and Antimalarial Agents
Research indicates its use in synthesising quinoline derivatives exhibiting antimicrobial activity and in the development of potential antimalarial agents.
| Molecular weight | 168.24 |
|---|---|
| Empirical formula | C9H16N2O |
| Assay | 98% |
| Boiling point | 100-115 °C/0.15-0.20 mmHg(lit.) |
| Application | Reactant for synthesis of:• Selective adenosine A2A receptor antagonists1• Antidepressents2• Small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells3• Orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation4• Quinoline derivatives with antimicrobial activity5• Antimalarials6 |
| Melting point | 40-43 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Morpholinopiperidine used for?
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4-Morpholinopiperidine (CAS: 53617-35-9) is used as a reactant in the synthesis of selective adenosine A2A receptor antagonists, antidepressants, small molecules targeting colorectal carcinoma cells, orally bioavailable P2Y12 antagonists, quinoline derivatives with antimicrobial activity, and antimalarials.
What are the CAS number and formula for 4-Morpholinopiperidine?
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The CAS number for 4-Morpholinopiperidine is 53617-35-9, and its empirical formula is C9H16N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Morpholinopiperidine with an assay of 98%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-Morpholinopiperidine be handled?
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4-Morpholinopiperidine is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator. Ensure adequate ventilation.
Is 4-Morpholinopiperidine a controlled substance?
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The provided data does not indicate that 4-Morpholinopiperidine is a controlled substance.
How is 4-Morpholinopiperidine packed and shipped?
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4-Morpholinopiperidine is carefully packed for safe handling and export, adhering to international shipping regulations for chemical substances.
How can I request a sample or quote for 4-Morpholinopiperidine?
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To request a sample or a quote for 4-Morpholinopiperidine, please contact our sales team through the website or by phone.
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