3,4,5-Trifluorobenzenesulfonyl chloride
3,4,5-Trifluorobenzenesulfonyl chloride (CAS: 351003-43-5) is a fluorinated organic compound with the molecular formula F3C6H2SO2Cl and a molecular weight of 230.59 g/mol. This reactive sulfonyl chloride is primarily employed as a building block in organic synthesis, particularly for introducing the 3,4,5-trifluorobenzenesulfonyl group into target molecules. Its unique fluorination pattern makes it valuable in the development of advanced materials and complex organic structures.
- Synonyms
- 351003-43-5F3C6H2SO2Cl
Organic Synthesis Reagent
Serves as a key intermediate for introducing the 3,4,5-trifluorobenzenesulfonyl moiety in various organic transformations. This enables the synthesis of complex molecules with tailored electronic and physical properties.
Pharmaceutical Intermediate
Utilised in the development pathways for novel pharmaceutical agents where the incorporation of fluorinated aromatic rings is desired. Fluorine atoms can enhance metabolic stability and binding affinity of drug candidates.
Materials Science Building Block
A valuable component in the synthesis of specialised polymers and advanced materials. The trifluorinated phenyl ring can influence material properties such as thermal stability and dielectric constants.
| Molecular weight | 230.59 |
|---|---|
| Linear formula | F3C6H2SO2Cl |
| Assay | 97% |
| Boiling point | 76-77 °C(lit.) |
| Density | 1.658 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4970(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 23 °C / 73.4 °F |
| Transport (UN / ADR) | UN 2924 8(3) / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-34 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4,5-Trifluorobenzenesulfonyl chloride used for?
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3,4,5-Trifluorobenzenesulfonyl chloride is primarily used as a building block in organic synthesis for introducing the 3,4,5-trifluorobenzenesulfonyl group into target molecules, finding applications in pharmaceuticals and materials science.
What is the CAS number and formula for 3,4,5-Trifluorobenzenesulfonyl chloride?
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The CAS number is 351003-43-5 and the linear formula is F3C6H2SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,4,5-Trifluorobenzenesulfonyl chloride with a minimum assay of 97%. This product is not represented as USP, BP, EP, or pharmacopoeia grade.
How should 3,4,5-Trifluorobenzenesulfonyl chloride be handled safely?
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This compound is dangerous and reacts violently with water, is flammable, and causes severe skin burns and eye damage. Handle with extreme caution, wearing appropriate personal protective equipment including eye protection, gloves, and respiratory protection. Ensure adequate ventilation and avoid contact with moisture.
How is this chemical packed and shipped?
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This chemical is packed and shipped according to international regulations for hazardous materials, including UN 2924, Hazard Class 8(3), Packing Group III, reflecting its corrosive and flammable nature. TSS is a specialist global supplier and exporter.
How can I request a quote or sample?
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To request a quote or sample of 3,4,5-Trifluorobenzenesulfonyl chloride, please use the contact form on our website or call our sales team directly.
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