3,4,5-Trifluorobenzonitrile
3,4,5-Trifluorobenzonitrile (CAS 134227-45-5) is a halogenated aromatic nitrile with the molecular formula F₃C₆H₂CN and a molecular weight of 157.09 g/mol. This compound serves as a valuable building block in organic synthesis, particularly within the C6 to C7 carbon range. Its chemical structure, featuring three fluorine atoms and a nitrile group on a benzene ring, makes it useful for introducing specific functionalities into more complex molecules.
- Synonyms
- 134227-45-5F3C6H2CN
Organic Synthesis Intermediate
3,4,5-Trifluorobenzonitrile is utilized as a key intermediate in the synthesis of various organic compounds. Its reactive nitrile group and fluorinated aromatic ring allow for diverse chemical transformations.
Pharmaceutical Building Block
The compound can serve as a precursor in the development of pharmaceutical agents. The trifluorinated phenyl moiety is incorporated into drug candidates to modulate their pharmacokinetic and pharmacodynamic properties.
Agrochemical Research
It finds application in the research and development of novel agrochemicals. The unique electronic properties imparted by the fluorine atoms can influence the biological activity of pesticides and herbicides.
Materials Science
3,4,5-Trifluorobenzonitrile may be employed in the synthesis of advanced materials. Its structure can contribute to the development of polymers or functional materials with specific electronic or thermal characteristics.
| Molecular weight | 157.09 |
|---|---|
| Linear formula | F3C6H2CN |
| Assay | 99% |
| Boiling point | 72-73 °C/10 mmHg(lit.) |
| Melting point | 45-47 °C(lit.) |
Hazard statements
- H228Flammable solid
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 62 °C / 143.6 °F |
| Transport (UN / ADR) | UN 1325 4.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F |
| Risk statements (R) | 11 |
| Safety statements (S) | 16-33 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4,5-Trifluorobenzonitrile used for?
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3,4,5-Trifluorobenzonitrile is primarily used as a building block and intermediate in organic synthesis, including applications in pharmaceutical research, agrochemical development, and potentially materials science.
What are the CAS number and chemical formula for 3,4,5-Trifluorobenzonitrile?
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The CAS number for 3,4,5-Trifluorobenzonitrile is 134227-45-5, and its linear chemical formula is F₃C₆H₂CN.
What grade and purity does Tech Serve Solutions supply for 3,4,5-Trifluorobenzonitrile?
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Tech Serve Solutions supplies 3,4,5-Trifluorobenzonitrile with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should 3,4,5-Trifluorobenzonitrile be handled safely?
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3,4,5-Trifluorobenzonitrile is a flammable solid (H228) requiring careful handling. It is essential to use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator (e.g., N100 US type). Store away from ignition sources and handle in a well-ventilated area.
How is 3,4,5-Trifluorobenzonitrile typically packed and shipped?
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3,4,5-Trifluorobenzonitrile is packed according to safety regulations for flammable solids (UN 1325, Class 4.1, PGII). TSS can export this chemical globally, adhering to all relevant international shipping standards.
How can I request a quote or sample for 3,4,5-Trifluorobenzonitrile?
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To request a quote or sample of 3,4,5-Trifluorobenzonitrile, please contact our sales department through the website or by phone. Provide your requirements, and we will respond promptly.
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