2-Fluoro-5-methoxybenzaldehyde
2-Fluoro-5-methoxybenzaldehyde (CAS: 105728-90-3), with the molecular formula FC6H3(OCH3)CHO and a molar mass of 154.14 g/mol, is a fluorinated aromatic aldehyde. It serves as a valuable building block in organic synthesis, particularly for introducing fluorinated methoxybenzoyl moieties into complex molecules. Its reactivity makes it a useful intermediate in the preparation of various chemical compounds across research and development sectors.
- IUPAC
- 6-Fluoro-m-anisaldehyde
- Synonyms
- 6-Fluoro-m-anisaldehyde

Organic Synthesis Intermediate
This compound is employed as a key intermediate in multi-step organic syntheses. It is used to construct more complex molecules through reactions involving its aldehyde functionality and the activated aromatic ring.
Pharmaceutical Research
As a fluorinated building block, 2-Fluoro-5-methoxybenzaldehyde can be incorporated into potential drug candidates. The presence of fluorine can influence pharmacokinetic properties such as metabolic stability and lipophilicity.
Materials Science
The unique electronic and structural properties conferred by the fluorine and methoxy substituents make this aldehyde a potential precursor for novel materials in areas like organic electronics or specialty polymers.
| Molecular weight | 154.14 |
|---|---|
| Linear formula | FC6H3(OCH3)CHO |
| Assay | 97% |
| Boiling point | 229-230 °C(lit.) |
| Density | 1.237 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.532(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 108 °C / 226.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-5-methoxybenzaldehyde used for?
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2-Fluoro-5-methoxybenzaldehyde is primarily used as a building block and intermediate in organic synthesis, particularly in the development of pharmaceuticals and novel materials.
What are the CAS number and formula for 2-Fluoro-5-methoxybenzaldehyde?
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The CAS number is 105728-90-3, and the linear formula is FC6H3(OCH3)CHO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-5-methoxybenzaldehyde with a minimum assay of 97%. This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Fluoro-5-methoxybenzaldehyde be handled?
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Handle with care. This compound is a warning hazard (GHS07) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Always use appropriate personal protective equipment, including eyeshields and gloves, and ensure adequate ventilation or use a respirator.
Is 2-Fluoro-5-methoxybenzaldehyde exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Fluoro-5-methoxybenzaldehyde.
How can I request a sample or quote for 2-Fluoro-5-methoxybenzaldehyde?
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To request a sample or a quote, please contact our sales department through the website or by phone, providing the product name and CAS number (105728-90-3).
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