2-Fluoro-5-methylaniline
2-Fluoro-5-methylaniline (CAS 452-84-6), with the molecular formula C7H8FN, is a fluorinated aromatic amine. This compound serves as a valuable building block in organic synthesis. It is primarily utilized in the research and development sectors, particularly within pharmaceutical and agrochemical industries, for the construction of more complex molecular structures. Its specific substitution pattern makes it a sought-after intermediate for creating targeted functional molecules.
- IUPAC
- 6-Fluoro-m-toluidine
- Synonyms
- 6-Fluoro-m-toluidine
Pharmaceutical Intermediate
2-Fluoro-5-methylaniline is employed as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its fluorinated structure can influence the pharmacokinetic and pharmacodynamic properties of the final drug molecule.
Agrochemical Synthesis
This compound finds application in the development of novel agrochemicals, such as pesticides and herbicides. The incorporation of fluorine can enhance the efficacy and stability of these agricultural products.
Organic Building Block
As a versatile organic building block, 2-Fluoro-5-methylaniline is used in academic and industrial research for creating a wide array of complex organic molecules and functional materials.
| Molecular weight | 125.14 |
|---|---|
| Linear formula | FC6H3(CH3)NH2 |
| Assay | 99% |
| Boiling point | 80-86 °C/11 mmHg(lit.) |
| Density | 1.109 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.533(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 82 °C / 179.6 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-5-methylaniline used for?
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2-Fluoro-5-methylaniline is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals.
What are the CAS number and formula for 2-Fluoro-5-methylaniline?
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The CAS number for 2-Fluoro-5-methylaniline is 452-84-6, and its molecular formula is C7H8FN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-5-methylaniline with a purity of 99% (assay). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
How should 2-Fluoro-5-methylaniline be handled safely?
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2-Fluoro-5-methylaniline is classified as a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, must be used. Handle in a well-ventilated area.
How is 2-Fluoro-5-methylaniline shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals. 2-Fluoro-5-methylaniline is shipped according to international regulations for hazardous materials, adhering to classifications such as NA 1993, PGIII.
How can I request a quote or sample for 2-Fluoro-5-methylaniline?
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To request a quote or a sample of 2-Fluoro-5-methylaniline, please contact our sales team through the TSS website or your designated account manager.
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