2-Fluoro-5-methoxyphenylboronic acid
2-Fluoro-5-methoxyphenylboronic acid (CAS: 406482-19-7; Formula: FC6H3(OCH3)B(OH)2) is a disubstituted aryl boronic acid with a molecular weight of 169.95 g/mol. It serves as a valuable reactant in organic synthesis, particularly in cross-coupling reactions. Its utility is demonstrated in the synthesis of complex organic molecules, including those investigated for use as molecular switches and in Friedel-Crafts alkylations. TSS supplies this compound for research and chemical synthesis purposes.
Suzuki-Miyaura Cross-Coupling
This aryl boronic acid is a key participant in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds with aryl or vinyl halides. This is a fundamental transformation in the synthesis of complex organic molecules.
Friedel-Crafts Alkylation
2-Fluoro-5-methoxyphenylboronic acid can be employed as a reactant in Friedel-Crafts alkylation processes. Specifically, it has been used in the alkylation of hydronaphthalenes, facilitating the introduction of functionalised aryl groups.
Synthesis of Molecular Switches
The compound is involved in the synthesis of molecules such as 9,10-diarylanthracenes, which are explored for their potential applications as molecular switches. This highlights its role in advanced materials research.
Cross-Coupling with Halides
It participates in cross-coupling reactions with various carbazolyl or aryl halides. This broadens its applicability in constructing diverse organic frameworks.
| Molecular weight | 169.95 |
|---|---|
| Linear formula | FC6H3(OCH3)B(OH)2 |
| Assay | ≥95% |
| Application | Reactant involved in:• Friedel-Crafts alkylation of hydronaphthalenes1• Suzuki-Miyaura cross-coupling reactions2,3• Synthesis of 9,10-diarylanthracenes for use as molecular switches4• Cross-coupling with carbazolyl or aryl halides5 |
| Melting point | 194-196 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-5-methoxyphenylboronic acid used for?
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2-Fluoro-5-methoxyphenylboronic acid is primarily used as a reactant in organic synthesis, including Suzuki-Miyaura cross-coupling reactions, Friedel-Crafts alkylations, and the synthesis of materials like molecular switches.
What is the CAS number and formula for this compound?
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The CAS number is 406482-19-7 and the molecular formula is FC6H3(OCH3)B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-5-methoxyphenylboronic acid with an assay of ≥95%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling considerations for this chemical?
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This compound is classified under WGK 3 in Germany. Appropriate personal protective equipment, including eyeshields and gloves, should be worn. A type N95 (US) or type P1 (EN143) respirator filter is recommended when handling.
How is 2-Fluoro-5-methoxyphenylboronic acid shipped and exported?
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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, adhering to all relevant shipping and export regulations.
How can I request a quote or sample?
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To request a quote or a sample of 2-Fluoro-5-methoxyphenylboronic acid, please contact the Tech Serve Solutions sales team through our website or by phone.
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