2-Fluoro-5-iodophenylboronic acid

CAS 866683-41-2FC6H3(I)B(OH)2Chemical Synthesis

2-Fluoro-5-iodophenylboronic acid (CAS: 866683-41-2) is a disubstituted aryl boronic acid with the formula FC₆H₃(I)B(OH)₂ and a molecular weight of 265.82 g/mol. This organometallic reagent is primarily utilised in organic synthesis, particularly in cross-coupling reactions. Its unique structure, featuring both fluorine and iodine substituents, makes it a valuable building block for creating complex organic molecules in pharmaceutical and materials science research.

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2-Fluoro-5-iodophenylboronic acid (FC6H3(I)B(OH)2) — chemical structure, CAS 866683-41-2; Chemistry, fine chemical supplied by Tech Serve Solutions

Aryl Boronic AcidsBoronic AcidsChemical Synthesis

01 /Applications

Suzuki-Miyaura Cross-Coupling Reactions

This compound serves as a key coupling partner in Suzuki-Miyaura reactions, enabling the formation of carbon-carbon bonds. It is used to introduce the 2-fluoro-5-iodophenyl moiety into diverse organic structures.

Organic Synthesis Building Block

As a versatile intermediate, it facilitates the synthesis of complex organic molecules. The presence of both fluoro and iodo groups offers distinct reactivity for further functionalisation.

Pharmaceutical Intermediate

It is employed in the research and development of new pharmaceutical agents. Its structure can be incorporated into drug candidates targeting various therapeutic areas.

Materials Science Research

2-Fluoro-5-iodophenylboronic acid can be used in the synthesis of novel organic materials with specific electronic or optical properties.

02 /Properties

Molecular weight	265.82
Linear formula	FC6H3(I)B(OH)2
Melting point	>230 °C(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

866683-41-2

MDL number

MFCD05664304

PubChem substance

24881442

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Fluoro-5-iodophenylboronic acid used for?

2-Fluoro-5-iodophenylboronic acid is used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, and as an intermediate in pharmaceutical and materials science research.

What is the CAS number and formula for 2-Fluoro-5-iodophenylboronic acid?

The CAS number is 866683-41-2 and the linear formula is FC₆H₃(I)B(OH)₂.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product for research and chemical synthesis purposes. We do not represent it as USP, EP, BP, or other pharmacopoeial grades. Please refer to the Certificate of Analysis for specific lot purity.

How should 2-Fluoro-5-iodophenylboronic acid be handled?

Handle with appropriate personal protective equipment, including eyeshields and gloves. Use a type N95 (US) or type P1 (EN143) respirator filter. It is classified under WGK Germany 3.