2-Fluoro-5-iodobenzonitrile
2-Fluoro-5-iodobenzonitrile (CAS 351003-36-6) is an organic compound with the linear formula C6H3FIN. Possessing a molecular weight of 247.01 g/mol, this fluorinated aromatic nitrile serves as a valuable building block in organic synthesis. Its structure, featuring both fluorine and iodine substituents on a benzonitrile core, allows for diverse chemical transformations. It is primarily utilised in research and development settings for the creation of complex molecules.

Organic Synthesis Intermediate
As a difunctionalised aromatic compound, 2-Fluoro-5-iodobenzonitrile is employed as a versatile intermediate in the synthesis of more complex organic molecules. The presence of the nitrile group and the iodine atom allows for various coupling reactions and nucleophilic substitutions.
Fluorinated Building Block
This compound belongs to the class of fluorinated building blocks, which are crucial in medicinal chemistry and materials science. The incorporation of fluorine can significantly alter the pharmacokinetic and physicochemical properties of target molecules.
Research and Development
2-Fluoro-5-iodobenzonitrile is used in laboratory settings for exploring new synthetic routes and developing novel chemical entities across various scientific disciplines.
| Molecular weight | 247.01 |
|---|---|
| Linear formula | C6H3FICN |
| Assay | 97% |
| Melting point | 72-76 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-5-iodobenzonitrile used for?
+
2-Fluoro-5-iodobenzonitrile is primarily used as an intermediate and building block in organic synthesis, particularly in research and development for creating complex organic molecules and exploring fluorinated compounds.
What is the CAS number and formula for 2-Fluoro-5-iodobenzonitrile?
+
The CAS number for 2-Fluoro-5-iodobenzonitrile is 351003-36-6, and its linear formula is C6H3FIN.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-Fluoro-5-iodobenzonitrile with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should 2-Fluoro-5-iodobenzonitrile be handled?
+
2-Fluoro-5-iodobenzonitrile is classified with Warning signal word and hazard statements H302, H312, H332. Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid contact with skin, eyes, and clothing.
Is 2-Fluoro-5-iodobenzonitrile shipped internationally?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Fluoro-5-iodobenzonitrile, and can facilitate international shipments.
How can I request a quote or sample?
+
To request a quote or sample of 2-Fluoro-5-iodobenzonitrile, please contact our sales department through the website or by phone. Details are available in the contact section.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis