Ethyl 4,4,4-trifluoro-2-butynoate
Ethyl 4,4,4-trifluoro-2-butynoate (CAS 79424-03-6) is a fluorinated ester with the linear formula CF₃C≡CCO₂C₂H₅ and a molecular weight of 166.10 g/mol. This compound serves as a versatile building block in organic synthesis. Its trifluoromethyl group and alkyne functionality offer unique reactivity for constructing complex molecules, particularly in pharmaceutical and materials science research.
- Synonyms
- 79424-03-6CF3C≡CCO2C2H5
Organic Synthesis Intermediate
Ethyl 4,4,4-trifluoro-2-butynoate is employed as a key intermediate in the synthesis of various organic compounds. Its electrophilic alkyne moiety readily participates in cycloaddition and nucleophilic addition reactions.
Fluorinated Compound Synthesis
This ester is valuable for introducing the trifluoromethyl group into target molecules. The presence of fluorine can significantly alter the electronic and steric properties of compounds, influencing their biological activity and physical characteristics.
Research and Development
It is utilized in academic and industrial R&D settings for the exploration of novel chemical structures and reaction pathways. Its specific reactivity makes it a useful reagent for probing reaction mechanisms and developing new synthetic methodologies.
| Molecular weight | 166.10 |
|---|---|
| Linear formula | CF3C≡CCO2C2H5 |
| Assay | ≥95.0% (GC) |
| Boiling point | 96-98 °C(lit.) |
| Density | 1.162 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.350(lit.)n20/D 1.350 |
Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 6 °C / 42.8 °F |
| Transport (UN / ADR) | UN 3272 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl 4,4,4-trifluoro-2-butynoate used for?
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Ethyl 4,4,4-trifluoro-2-butynoate is primarily used as an intermediate in organic synthesis, particularly for introducing trifluoromethyl groups into molecules and in the development of novel fluorinated compounds for research purposes.
What are the CAS number and formula for Ethyl 4,4,4-trifluoro-2-butynoate?
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The CAS number is 79424-03-6, and its linear formula is CF₃C≡CCO₂C₂H₅.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl 4,4,4-trifluoro-2-butynoate with a purity of ≥95.0% (GC). We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
How should Ethyl 4,4,4-trifluoro-2-butynoate be handled?
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This compound is a flammable liquid and vapour (H225), causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including safety glasses, gloves, and a respirator, in a well-ventilated area, away from ignition sources.
Is Ethyl 4,4,4-trifluoro-2-butynoate packed and exported by TSS?
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Yes, Tech Serve Solutions exports and supplies Ethyl 4,4,4-trifluoro-2-butynoate globally.
How can I request a quote or sample for Ethyl 4,4,4-trifluoro-2-butynoate?
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Please contact our sales team directly via the website or phone to request a quotation or a sample of Ethyl 4,4,4-trifluoro-2-butynoate.
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