Ethyl 4,4-difluoroacetoacetate
Ethyl 4,4-difluoroacetoacetate (CAS 352-24-9), with the molecular formula C6H8F2O3 and a molecular weight of 166.12 g/mol, is a valuable fluorinated organic compound. It serves as a key building block in organic synthesis, particularly in the preparation of complex molecules. Its difluoroacetoacetate structure allows for versatile chemical transformations, making it a useful intermediate in various chemical research and development applications.
- IUPAC
- 4,4-Difluoro-3-oxobutanoic acid ethyl ester,4,4-Difluoro-3-oxobutyric acid ethyl ester,4,4-Difluoroacetoacetic acid ethyl ester,Ethyl 4,4-difluoro-3-ketobutyrate,Ethyl 4,4-difluoro-3-oxobutanoate,Ethyl 4,4-difluoro-3-oxobutyrate
- Synonyms
- 4,4-Difluoro-3-oxobutanoic acid ethyl ester4,4-Difluoro-3-oxobutyric acid ethyl ester4,4-Difluoroacetoacetic acid ethyl esterEthyl 4,4-difluoro-3-ketobutyrateEthyl 4,4-difluoro-3-oxobutanoateEthyl 4,4-difluoro-3-oxobutyrate
Pharmaceutical Intermediate
This compound is utilised in the synthesis of novel pharmaceutical agents. Its fluorinated nature can impart desirable properties to drug candidates, influencing factors like metabolic stability and lipophilicity.
Agrochemical Synthesis
Ethyl 4,4-difluoroacetoacetate can serve as a precursor in the development of new agrochemicals. The introduction of fluorine atoms is a common strategy to enhance the efficacy and selectivity of pesticides and herbicides.
Organic Building Block
As a versatile C6 building block, it is employed in diverse organic synthesis pathways for creating complex fluorinated molecules. Its reactive functional groups allow for a range of chemical modifications.
Research and Development
This chemical is frequently used in academic and industrial research laboratories for exploring new synthetic methodologies and discovering novel compounds with potential applications.
| Molecular weight | 166.12 |
|---|---|
| Empirical formula | C6H8F2O3 |
| Assay | 98% |
| Density | 1.269 g/mL at 25 °C |
| Refractive index | n20/D 1.409 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Flash point | 68 °C / 154.4 °F |
|---|---|
| Transport (UN / ADR) | UN 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl 4,4-difluoroacetoacetate used for?
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Ethyl 4,4-difluoroacetoacetate (CAS 352-24-9) is primarily used as a building block in organic synthesis, including the development of pharmaceuticals and agrochemicals.
What is the CAS number and molecular formula for Ethyl 4,4-difluoroacetoacetate?
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The CAS number is 352-24-9 and the molecular formula is C6H8F2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl 4,4-difluoroacetoacetate with an assay of 98%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
How should Ethyl 4,4-difluoroacetoacetate be handled?
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Ethyl 4,4-difluoroacetoacetate is classified as an irritant. Handle with appropriate personal protective equipment, including gloves and eye protection, in a well-ventilated area. Avoid contact with skin and eyes. Refer to the Safety Data Sheet (SDS) for detailed handling information.
Is this product shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and can export Ethyl 4,4-difluoroacetoacetate worldwide.
How can I request a quotation or sample?
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To request a quotation or sample of Ethyl 4,4-difluoroacetoacetate, please contact our sales team through the website or by phone.
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