2,6-Difluorobenzylamine
2,6-Difluorobenzylamine (CAS 69385-30-4) is an organic compound with the linear formula F2C6H3CH2NH2 and a molecular weight of 143.13 g/mol. This fluorinated benzylamine derivative serves as a valuable building block in organic synthesis, particularly in the development of complex molecules within the pharmaceutical and chemical industries. Its structure lends itself to various synthetic transformations.
- Synonyms
- F2C6H3CH2NH2
Synthesis of Amidines
2,6-Difluorobenzylamine is utilised in the synthesis of amidine derivatives, such as (Z)-N1-(2,6-difluorobenzyl)-N2-(2-amino-1,2-dicyanovinyl)formamidine. This highlights its utility in constructing nitrogen-containing heterocyclic compounds.
Preparation of Guanidine Salts
The compound has been employed in the preparation of guanidine salts, including 2,6-difluorobenzyl-guanidine hydrochloride. This application demonstrates its role as a precursor for guanidine-based structures.
Fluorinated Organic Building Block
As a fluorinated aromatic amine, 2,6-difluorobenzylamine functions as a versatile building block. The presence of fluorine atoms can impart unique electronic and lipophilic properties to target molecules.
| Molecular weight | 143.13 |
|---|---|
| Linear formula | F2C6H3CH2NH2 |
| Assay | 97% |
| Density | 1.197 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.493(lit.) |
| Application | 2,6-Difluorobenzylamine has been used in the synthesis of:• (Z)-N1-(2,6-difluorobenzyl)-N2-(2-amino-1,2-dicyanovinyl)formamidine1• 2,6-difluorobenzyl-guanidine hydrochloride2 |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 66 °C / 150.8 °F |
| Transport (UN / ADR) | UN 2735 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,6-Difluorobenzylamine used for?
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2,6-Difluorobenzylamine is used as a building block in organic synthesis for preparing compounds such as amidines and guanidine salts, and in general chemical synthesis involving fluorinated aromatic amines.
What is the CAS number and formula for 2,6-Difluorobenzylamine?
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The CAS number is 69385-30-4 and the linear formula is F2C6H3CH2NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,6-Difluorobenzylamine with an assay of 97%. This is a technical or research grade, and TSS does not represent it as USP, BP, or EP grade.
What are the primary hazards associated with 2,6-Difluorobenzylamine?
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2,6-Difluorobenzylamine is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including gloves, goggles, and respiratory protection, is required.
How is 2,6-Difluorobenzylamine typically packed and shipped?
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This chemical is transported under UN 2735, hazard class 8, packing group 3. TSS adheres to all regulations for safe packing, shipping, and export of chemical products.
How can I request a sample or quote for 2,6-Difluorobenzylamine?
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To request a sample or quote, please contact the Tech Serve Solutions sales team through our website or by phone.
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