2,6-Difluorophenol
2,6-Difluorophenol (CAS: 28177-48-2; F₂C₆H₃OH) is a fluorinated organic building block with a molecular weight of 130.09 g/mol. This compound serves as a key intermediate in chemical synthesis, particularly in the development of advanced materials. It is recognised for its utility in polymer science, undergoing oxidative polymerisation to form poly(2,6-difluoro-1,4-phenylene oxide). TSS supplies this chemical with a minimum assay of 98%.
- Synonyms
- F2C6H3OH

Polymer Synthesis
2,6-Difluorophenol is used as a monomer in oxidative polymerisation reactions. Catalysed by metal complexes and oxidising agents, it can be converted into poly(2,6-difluoro-1,4-phenylene oxide).
Organic Synthesis Intermediate
As a functionalised aromatic compound, it serves as a versatile building block in the synthesis of more complex organic molecules for research and development.
Fluorinated Materials Development
The presence of fluorine atoms makes this compound valuable for creating materials with specific properties, such as enhanced thermal stability or altered electronic characteristics.
| Molecular weight | 130.09 |
|---|---|
| Linear formula | F2C6H3OH |
| Assay | 98% |
| Boiling point | 59-61 °C/17 mmHg(lit.) |
| Solubility | ethanol: soluble50 mg/mL, clear, colorless to light yellow |
| Application | 2,6-difluorophenol undergoes oxidative polymerization in the presence of the Fe-N,N′-bis(salicylidene)ethylenediamine (salen) complex (catalyst) and hydrogen peroxide (oxidizing agent) to give poly(2,6-difluoro-1,4-phenylene oxide)1. |
| Melting point | 38-41 °C(lit.) |


Hazard statements
- H228Flammable solid
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 58 °C / 136.4 °F |
| Transport (UN / ADR) | UN 1325 4.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,6-Difluorophenol used for?
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2,6-Difluorophenol is primarily used as a monomer in the synthesis of polymers like poly(2,6-difluoro-1,4-phenylene oxide) and as a general intermediate in organic synthesis.
What is the CAS number and chemical formula for 2,6-Difluorophenol?
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The CAS number for 2,6-Difluorophenol is 28177-48-2 and its linear formula is F₂C₆H₃OH.
What grade and purity does Tech Serve Solutions supply for 2,6-Difluorophenol?
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Tech Serve Solutions supplies 2,6-Difluorophenol with a minimum purity of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated otherwise in the product documentation.
How should 2,6-Difluorophenol be handled safely?
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2,6-Difluorophenol is a flammable solid (H228) and an irritant to the skin, eyes, and respiratory tract (H315, H319, H335). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, must be used. Ensure good ventilation and keep away from ignition sources.
How is 2,6-Difluorophenol packed and shipped?
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2,6-Difluorophenol is packed and shipped according to relevant dangerous goods regulations, designated as UN 1325, Hazard Class 4.1, Packing Group II.
How can I request a quote or sample of 2,6-Difluorophenol?
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To request a quote or sample of 2,6-Difluorophenol, please contact our sales team through the website or via direct inquiry.
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