2,6-Difluorophenylacetic acid
2,6-Difluorophenylacetic acid (CAS 85068-28-6) is a fluorinated organic compound with the linear formula F₂C₆H₃CH₂CO₂H and a molecular weight of 172.13 g/mol. This carboxylic acid serves as a valuable building block in organic synthesis. It is primarily utilised in the preparation of more complex molecules, including pharmaceutical intermediates and specialty chemicals, leveraging the unique properties imparted by the difluorophenyl moiety. Available at 97% purity, it is supplied by Tech Serve Solutions for research and development purposes.
- Synonyms
- F2C6H3CH2CO2H
Synthesis of α-azidoacetophenones
2,6-Difluorophenylacetic acid has been employed as a precursor in the synthesis of α-azidoacetophenones, which are intermediates potentially useful in further chemical transformations.
Preparation of Urea Derivatives
This compound has been documented for its use in synthesising urea derivatives, such as N-(2,6-difluorobenzyl)-N′- (1H-5-indazolyl)urea, highlighting its utility in medicinal chemistry research.
Fluorinated Organic Building Block
As a fluorinated building block, 2,6-difluorophenylacetic acid is integral to introducing difluorophenyl groups into organic molecules, a strategy often used to modulate physicochemical and biological properties.
| Molecular weight | 172.13 |
|---|---|
| Linear formula | F2C6H3CH2CO2H |
| Assay | 97% |
| Application | 2,6-Difluorophenylacetic acid has been used in the synthesis of:• α-azidoacetophenones1• N-(2,6-difluorobenzyl)-N′-(1H-5-indazolyl)urea2 |
| Melting point | 100-102 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,6-Difluorophenylacetic acid used for?
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2,6-Difluorophenylacetic acid is primarily used as a building block in organic synthesis for creating more complex molecules, including intermediates for pharmaceuticals and specialty chemicals. It has been specifically used in the synthesis of α-azidoacetophenones and certain urea derivatives.
What are the CAS number and molecular formula for 2,6-Difluorophenylacetic acid?
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The CAS number for 2,6-Difluorophenylacetic acid is 85068-28-6. Its linear molecular formula is F₂C₆H₃CH₂CO₂H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,6-Difluorophenylacetic acid with an assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated in the product data.
How should 2,6-Difluorophenylacetic acid be handled safely?
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Based on the provided safety data, 2,6-Difluorophenylacetic acid is a warning substance that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves, should be used. Ensure adequate ventilation and avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes.
Is 2,6-Difluorophenylacetic acid a controlled substance?
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The provided data does not indicate that 2,6-Difluorophenylacetic acid is a controlled substance.
How is 2,6-Difluorophenylacetic acid packed and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, packs and ships chemicals according to international regulations to ensure safe transit worldwide.
How can I request a quote or sample for 2,6-Difluorophenylacetic acid?
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To request a quote or sample for 2,6-Difluorophenylacetic acid, please contact our sales team through the inquiry form on our website or by calling our customer service.
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