2,6-Difluoropyridine
2,6-Difluoropyridine (CAS: 1513-65-1) is a fluorinated heterocyclic building block with the molecular formula C5H3F2N and a molecular weight of 115.08 g/mol. This compound serves as a crucial intermediate in chemical synthesis, particularly for creating advanced materials. Its applications include the preparation of polymers, contributing to the development of specialized materials with unique properties.
- Synonyms
- C5H3F2N

Polymer Synthesis
2,6-Difluoropyridine is employed in the synthesis of poly(pyridine ether)s. This process involves polycondensation reactions with agents like silylated 1,1,1-tris(4-hydroxyphenyl)ethane, leading to novel polymeric materials.
Fluorinated Building Block
As a difluorinated pyridine derivative, it acts as a valuable building block in organic synthesis. It enables the introduction of the difluoropyridine moiety into larger molecular structures for research and development.
Chemical Intermediate
This compound functions as an important intermediate in the synthesis of various organic molecules. Its specific structure allows for diverse chemical transformations in the development of fine chemicals and pharmaceutical precursors.
| Molecular weight | 115.08 |
|---|---|
| Empirical formula | C5H3F2N |
| Assay | 99% |
| Boiling point | 124.5 °C/743 mmHg(lit.) |
| Density | 1.268 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.437(lit.) |
| Application | 2,6-Difluoropyridine has been used in the preparation of poly(pyridine ether)s via polycondensation with silylated 1,1,1-tris(4-hydroxyphenyl)ethane1. |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 33 °C / 91.4 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,6-Difluoropyridine used for?
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2,6-Difluoropyridine is primarily used as a building block in chemical synthesis, including the preparation of polymers like poly(pyridine ether)s. It serves as a key intermediate for introducing fluorinated heterocyclic structures into more complex molecules.
What are the CAS number and molecular formula for 2,6-Difluoropyridine?
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The CAS number for 2,6-Difluoropyridine is 1513-65-1, and its molecular formula is C5H3F2N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,6-Difluoropyridine with a minimum purity of 99% (assay). This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, EP, or other pharmacopoeia grades.
How should 2,6-Difluoropyridine be handled safely?
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2,6-Difluoropyridine is a flammable liquid and vapour (H226) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. Keep away from heat, sparks, and open flames.
Is 2,6-Difluoropyridine a controlled substance?
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Based on the provided data, there is no indication that 2,6-Difluoropyridine is a controlled substance.
How is 2,6-Difluoropyridine packed, shipped, and exported?
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2,6-Difluoropyridine is packaged and shipped in compliance with relevant transportation regulations, including UN 1993 classification for flammable liquids. As a global supplier, Tech Serve Solutions exports chemicals worldwide.
How can I request a quote or sample for 2,6-Difluoropyridine?
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To request a quote or sample for 2,6-Difluoropyridine, please contact our sales team through the website or by phone, providing your specific requirements.
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