Benzene-1,4-diboronic acid mono-MIDA ester
Benzene-1,4-diboronic acid mono-MIDA ester (CAS: 1104665-01-1) is a key organometallic reagent and a monosubstituted aryl boronate derivative. Its molecular formula is C11H13B2NO6 and it has a molecular weight of 276.85 g/mol. This compound is primarily utilised in organic synthesis, particularly in palladium-catalyzed cross-coupling reactions like the Suzuki-Miyaura coupling, owing to the stability and controlled reactivity imparted by the MIDA protecting group. It serves as a valuable building block for complex molecule construction.
- IUPAC
- Benzene-1-boronic acid-4-boronic acid MIDA ester
- Synonyms
- Benzene-1-boronic acid-4-boronic acid MIDA ester

Suzuki Cross-Coupling Reactions
Benzene-1,4-diboronic acid mono-MIDA ester is employed as a coupling partner in Suzuki-Miyaura cross-coupling reactions. The MIDA protecting group offers enhanced stability and allows for sequential couplings, making it ideal for the synthesis of polyarylated compounds.
Organic Synthesis Building Block
As a versatile aryl boronate derivative, this compound acts as a crucial building block in the construction of complex organic molecules. It is instrumental in medicinal chemistry and materials science for creating novel structures.
Catalysis Research
This reagent is used in research settings to explore new catalytic methodologies and synthetic pathways. Its defined structure and reactivity profile make it a reliable component in the development of advanced chemical processes.
| Molecular weight | 276.85 |
|---|---|
| Empirical formula | C11H13B2NO6 |
| Application | Suzuki Cross-Coupling with MIDA Boronates |
| Melting point | 170-175 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Benzene-1,4-diboronic acid mono-MIDA ester used for?
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Benzene-1,4-diboronic acid mono-MIDA ester is primarily used in organic synthesis, especially in Suzuki cross-coupling reactions, and as a building block for complex molecule construction.
What is the CAS number and formula for Benzene-1,4-diboronic acid mono-MIDA ester?
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The CAS number is 1104665-01-1 and the empirical formula is C11H13B2NO6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research or technical grade chemical. It is not supplied as USP, BP, or EP grade, and TSS does not represent it as such.
How should Benzene-1,4-diboronic acid mono-MIDA ester be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use a suitable respirator filter (e.g., type N95 or P1) if airborne exposure is possible. Refer to the safety data sheet for comprehensive handling instructions.
How is Benzene-1,4-diboronic acid mono-MIDA ester packed, shipped, and exported?
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This chemical is carefully packed to ensure integrity during transit. Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, adhering to all relevant shipping regulations for international delivery.
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales department through the website or by phone, providing the product name and CAS number.
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