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(−)-Menthol

CAS 2216-51-5C10H20OChemical Synthesis

(−)-Menthol (CAS: 2216-51-5, Formula: C10H20O) is a naturally occurring organic compound with a molecular weight of 156.27 g/mol. It is known for its characteristic minty aroma and cooling sensation. This crystalline solid finds extensive use as a flavouring agent, in aromatherapy, and as a key component in topical analgesics and decongestants due to its physiological effects.

IUPAC
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol,5-Methyl-2-(1-methylethyl)cyclohexanol
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(−)-Menthol (C10H20O) — chemical structure, CAS 2216-51-5; Chemistry, fine chemical supplied by Tech Serve Solutions
AlcoholsAnalytical/ChromatographyAsymmetric SynthesisCell BiologyChemical SynthesisChiral Building BlocksMetabolic PathwaysMetabolomicsOrganic Building BlocksPharmacopoeia
01 /Applications

Flavour and Fragrance Industry

Primarily used to impart a cooling sensation and minty flavour to confectionery, chewing gum, oral hygiene products, and perfumes. Its refreshing aroma makes it a staple in many fragrance compositions.

Pharmaceutical Applications

Incorporated into over-the-counter medications such as cough drops, throat lozenges, and topical creams for its analgesic and antipruritic properties. It provides a cooling sensation that can relieve minor pain and itching.

Aromatherapy and Personal Care

Utilised in aromatherapy for its invigorating scent and in personal care products like shampoos and lotions for its refreshing and soothing effects. It is also a common ingredient in balms and salves.

Chemical Synthesis

Serves as a chiral auxiliary and building block in asymmetric synthesis, enabling the stereoselective preparation of complex organic molecules. Its defined stereochemistry is valuable in stereospecific reactions.

02 /Properties
Molecular weight156.27
Empirical formulaC10H20O
Assay98.0-102.0%
Gradepuriss.
Boiling point212 °C(lit.)
Density0.89 g/mL at 25 °C(lit.)
Optical activity[α]20/D −48 to −51°, c = 10% in ethanol
Melting point41-44 °C
Vapour pressure0.8 mmHg (20 °C)
Impurities testedacidity or alcalinity, compliesrelated subst., complies≤0.05% non-volatile matter
Suitabilityin accordance for appearance of solution
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H315Causes skin irritation
  • H318Causes serious eye damage
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Flash point101 °C / 213.8 °F
Water hazard class (WGK, DE)2
Hazard codes (EU)Xi
Risk statements (R)37/38-41
Safety statements (S)26-39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
2216-51-5
MDL number
MFCD00062979
Beilstein registry
1902293
05 /Additional specifications
Qualitymeets analytical specification of Ph. Eur., BP, USP
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is (–)-Menthol used for?

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(–)-Menthol is used as a flavouring agent, in aromatherapy, and in pharmaceutical preparations for its cooling and analgesic properties. It is also employed as a chiral building block in chemical synthesis.

What is the CAS number and chemical formula for (–)-Menthol?

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The CAS number for (–)-Menthol is 2216-51-5, and its chemical formula is C10H20O.

What grade and purity does Tech Serve Solutions supply for (–)-Menthol?

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Tech Serve Solutions supplies (–)-Menthol with an assay of 98.0-102.0% and a puriss. grade. It meets analytical specifications for Ph. Eur., BP, and USP, with non-volatile matter ≤0.05%.

What are the main safety hazards associated with (–)-Menthol?

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(–)-Menthol is classified with GHS symbols GHS05 and GHS07, and the signal word is Danger. It carries hazard statements H315 (Causes skin irritation), H318 (Causes serious eye damage), and H335 (May cause respiratory irritation). Appropriate PPE, including a dust mask, eyeshields, and gloves, is recommended.

How is (–)-Menthol typically packed and exported by TSS?

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Tech Serve Solutions packs and exports (–)-Menthol according to international standards for chemical handling and shipping, ensuring product integrity and safety during transit.

How can I request a quote or sample of (–)-Menthol?

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To request a quote or sample of (–)-Menthol, please contact our sales department through the TSS website or by calling our customer service line.

Need (−)-Menthol in a specific grade or volume?