(−)-Menthoxyacetyl chloride
(−)-Menthoxyacetyl chloride (CAS: 15356-62-4, C12H21ClO2) is a chiral acid halide with a molecular weight of 232.75 g/mol. It is primarily employed as a valuable building block in asymmetric synthesis and general organic chemical synthesis. Its specific chirality and reactive acyl chloride functionality make it useful for introducing the menthoxyacetyl group into various molecules. This compound is supplied by TSS with an assay of 97%.

Chiral Building Block in Organic Synthesis
Utilised as a chiral synthon for the construction of complex organic molecules where stereochemical control is essential. Its reactive acyl chloride group readily undergoes reactions with nucleophiles.
Asymmetric Synthesis
Serves as a key intermediate in asymmetric synthesis methodologies, enabling the creation of enantiomerically enriched compounds. The inherent chirality of the menthoxy moiety influences the stereochemical outcome of reactions.
Derivatisation Reagent
Used to introduce the menthoxyacetyl functionality onto alcohols, amines, or other nucleophilic species. This can be useful for purification, characterisation, or modifying the properties of target molecules.
| Molecular weight | 232.75 |
|---|---|
| Empirical formula | C12H21ClO2 |
| Assay | 97% |
| Density | 1.033 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.469(lit.) |
| Optical activity | [α]25/D −10°, neat |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (–)-Menthoxyacetyl chloride used for?
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(–)-Menthoxyacetyl chloride is used as a chiral building block in organic synthesis and asymmetric synthesis. It is also employed as a derivatisation reagent to introduce the menthoxyacetyl group into molecules.
What are the CAS number and chemical formula for (–)-Menthoxyacetyl chloride?
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The CAS number is 15356-62-4 and the empirical formula is C12H21ClO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (–)-Menthoxyacetyl chloride with an assay of 97%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
What are the safety considerations for handling (–)-Menthoxyacetyl chloride?
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(–)-Menthoxyacetyl chloride is corrosive and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including faceshields, gloves, and respiratory protection, is mandatory. Handle in a well-ventilated area and seek immediate medical attention if exposure occurs.
How is (–)-Menthoxyacetyl chloride packed, shipped, and exported?
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This product is classified under UN 3265, Class 8, Packing Group III, indicating it is a corrosive solid, acidic, organic, n.o.s. (or liquid, depending on form). TSS adheres to strict international shipping regulations for hazardous materials.
How can I request a sample or quote for (–)-Menthoxyacetyl chloride?
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To request a sample or obtain a quotation, please contact our sales team through the website or directly via email, providing your specific requirements and delivery details.
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