(2,5-Dimethoxyphenyl)acetyl chloride
(2,5-Dimethoxyphenyl)acetyl chloride (CAS: 52711-92-9) is an organic compound with the linear formula (CH3O)2C6H3CH2COCl and a molecular weight of 214.65 g/mol. This acid chloride derivative serves as a valuable intermediate in organic synthesis, particularly in the preparation of various chemical entities. Its reactivity makes it useful in research and development settings for introducing the (2,5-dimethoxyphenyl)acetyl moiety into other molecules, contributing to the creation of novel compounds.
- Synonyms
- (2,5-Dimethoxyphenyl)acetyl chloride

Organic Synthesis Intermediate
This compound is employed as a key building block in multi-step organic synthesis. Its acyl chloride functionality readily reacts with nucleophiles, enabling the formation of esters, amides, and other derivatives.
Research and Development
Used in academic and industrial R&D laboratories for exploring new chemical pathways and developing novel molecules. Its specific structure allows for targeted functionalization in complex synthetic strategies.
Pharmaceutical Precursor
Potentially utilised in the synthesis of pharmaceutical intermediates, where the dimethoxyphenylacetyl group might be a structural feature of interest in drug discovery and development.
| Molecular weight | 214.65 |
|---|---|
| Linear formula | (CH3O)2C6H3CH2COCl |
| Assay | 99% |
| Boiling point | 118 °C/0.8 mmHg(lit.) |
| Density | 1.227 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5385(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 108 °C / 226.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 23-26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2,5-Dimethoxyphenyl)acetyl chloride used for?
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(2,5-Dimethoxyphenyl)acetyl chloride is primarily used as an intermediate in organic synthesis and for research and development purposes in laboratories, potentially serving as a precursor in pharmaceutical synthesis.
What is the CAS number and formula for (2,5-Dimethoxyphenyl)acetyl chloride?
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The CAS number is 52711-92-9 and the linear formula is (CH3O)2C6H3CH2COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (2,5-Dimethoxyphenyl)acetyl chloride with an assay of 99%. TSS does not represent this product as USP, BP, or EP grade.
How should (2,5-Dimethoxyphenyl)acetyl chloride be handled safely?
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This compound is corrosive (H314) and requires careful handling. Use appropriate personal protective equipment, including full-face respirators, gloves, goggles, and chemical-resistant clothing. Ensure adequate ventilation and follow emergency procedures as outlined in the safety data sheet.
How is this product packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports (2,5-Dimethoxyphenyl)acetyl chloride in compliance with all relevant regulations for hazardous materials. Packaging is designed to ensure product integrity and safety during transit.
How can I request a sample or a quote?
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To request a sample or a quote for (2,5-Dimethoxyphenyl)acetyl chloride, please contact our sales department through the website or by calling our office.
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