(2S,4R)-4-Methylglutamic acid
(2S,4R)-4-Methylglutamic acid (CAS: 31137-74-3) is a chemical compound with the empirical formula C6H11NO4 and a molecular weight of 161.16 g/mol. This white solid is primarily utilized in neuroscience research as an antagonist for AMPA and kainate receptors. Its specific stereochemistry makes it a valuable tool for studying excitatory amino acid neurotransmission and ionotropic glutamate receptor function in biological systems.
- IUPAC
- SYM-2081
- Synonyms
- (2S,4R)-4-Methylglutamic acid
Neuroscience Research
(2S,4R)-4-Methylglutamic acid serves as a crucial research chemical for investigating the roles of AMPA and kainate receptors in the central nervous system. Its antagonist properties aid in understanding excitatory neurotransmission and neuronal signaling pathways.
Receptor Antagonist Studies
This compound is employed to selectively block the activity of ionotropic glutamate receptors, specifically AMPA and kainate subtypes. This allows researchers to elucidate the downstream effects of receptor activation and blockade in cellular and animal models.
Cell Biology Investigations
As a bioactive small molecule, (2S,4R)-4-Methylglutamic acid is used in cell biology experiments to probe cellular responses related to excitotoxicity, synaptic plasticity, and neurodegenerative processes.
| Molecular weight | 161.16 |
|---|---|
| Empirical formula | C6H11NO4 |
| Form | solid |
| Colour | white |
| Solubility | H2O: >10 mg/mL |
| Optical activity | [α]23/D +23.2°, c = 0.73 in 6 M HCl(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2S,4R)-4-Methylglutamic acid used for?
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(2S,4R)-4-Methylglutamic acid is primarily used in neuroscience research as an antagonist for AMPA and kainate receptors, aiding in the study of excitatory neurotransmission and ionotropic glutamate receptor function.
What are the CAS number and formula for (2S,4R)-4-Methylglutamic acid?
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The CAS number for (2S,4R)-4-Methylglutamic acid is 31137-74-3, and its empirical formula is C6H11NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (2S,4R)-4-Methylglutamic acid typically as a research or technical grade chemical. We do not represent it as USP, BP, or EP grade unless explicitly stated in the product specifications.
What are the safety and handling recommendations for (2S,4R)-4-Methylglutamic acid?
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Handling (2S,4R)-4-Methylglutamic acid requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound has a WGK Germany rating of 3, indicating it is hazardous to water.
Is (2S,4R)-4-Methylglutamic acid a controlled substance?
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The provided data does not indicate that (2S,4R)-4-Methylglutamic acid is a controlled substance.
How is (2S,4R)-4-Methylglutamic acid packed and shipped?
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(2S,4R)-4-Methylglutamic acid is supplied as a solid. Packing and shipping procedures adhere to international regulations for chemical transport. TSS is a global supplier and exporter.
How can I request a sample or quote for (2S,4R)-4-Methylglutamic acid?
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To request a sample or quote for (2S,4R)-4-Methylglutamic acid, please contact the TSS sales department through our official website or designated contact channels.
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