Boc-Phe(3,5-F2)-OH

CAS 205445-52-95-F2)-OHChemical Synthesis

Boc-Phe(3,5-F2)-OH (CAS 205445-52-9) is a protected, unnatural amino acid derivative with the molecular formula C14H17F2NO4. This compound is crucial in chemical synthesis and peptide chemistry for introducing fluorinated phenylalanine residues into peptides and other complex molecules. Its unique structure allows for investigation in chemical biology and the development of novel pharmaceutical intermediates.

IUPAC: Boc-3,5-difluoro-L-phenylalanine
Synonyms: Boc-3,5-difluoro-L-phenylalanineN-tert-Butoxycarbonyl-3,5-difluorophenylalanine

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Boc-Phe(3,5-F2)-OH (5-F2)-OH) — chemical structure, CAS 205445-52-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesChemical BiologyChemical SynthesisPeptide ChemistryPhenylalaninePhenylalanine Derivatives

01 /Applications

Peptide Synthesis

Utilised in solid-phase and solution-phase peptide synthesis to incorporate fluorinated phenylalanine analogues, enabling studies on peptide structure-activity relationships and the development of peptidomimetics.

Chemical Biology Research

Serves as a building block for creating modified peptides and proteins to probe biological pathways, investigate enzyme mechanisms, or develop novel diagnostic and therapeutic agents.

Drug Discovery and Development

A key intermediate in the synthesis of novel pharmaceutical compounds, where the difluorinated phenylalanine moiety can enhance metabolic stability, receptor binding, or bioavailability.

Organic Synthesis

Employed as a versatile chiral building block in the synthesis of complex organic molecules, leveraging the protected amino acid functionality and the electron-withdrawing effects of the fluorine atoms.

02 /Properties

Molecular weight	301.29
Empirical formula	C14H17F2NO4
Assay	≥98.0% (HPLC)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

205445-52-9

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Boc-Phe(3,5-F2)-OH used for?

Boc-Phe(3,5-F2)-OH is used in peptide synthesis, chemical biology research, drug discovery, and organic synthesis as a building block for introducing fluorinated phenylalanine residues.

What is the CAS number and molecular formula for Boc-Phe(3,5-F2)-OH?

The CAS number is 205445-52-9 and the molecular formula is C14H17F2NO4.

What grade and purity does Tech Serve Solutions supply for Boc-Phe(3,5-F2)-OH?

Tech Serve Solutions supplies Boc-Phe(3,5-F2)-OH with an assay of ≥98.0% by HPLC. We do not represent this product as USP, BP, or EP grade.

What are the safety considerations when handling Boc-Phe(3,5-F2)-OH?

When handling Boc-Phe(3,5-F2)-OH, it is essential to use safety precautions including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The WGK Germany is 3.

How is Boc-Phe(3,5-F2)-OH packed, shipped, and exported by TSS?

As a specialist global supplier, TSS professionally packs, handles, and exports fine chemicals like Boc-Phe(3,5-F2)-OH worldwide, adhering to all relevant regulations for safe and secure transport.