Boc-Phe(3-CF3)-OH
Boc-Phe(3-CF3)-OH (CAS: 142995-31-1) is a trifluoromethylated phenylalanine derivative with the molecular formula C15H18F3NO4 and a molecular weight of 333.30. This unnatural amino acid derivative, featuring an N-Boc protecting group, is primarily utilised in chemical synthesis and peptide chemistry. Its unique structure makes it a valuable building block for creating complex peptides and other biologically active molecules.
- IUPAC
- Boc-3-(trifluoromethyl)-L-phenylalanine
- Synonyms
- Boc-3-(trifluoromethyl)-L-phenylalanine
Peptide Synthesis
Incorporated into peptide chains, Boc-Phe(3-CF3)-OH introduces a trifluoromethyl group, potentially altering the peptide's conformational stability, lipophilicity, and biological activity. It serves as a specialised building block in solid-phase or solution-phase peptide synthesis.
Chemical Synthesis
This compound acts as a chiral intermediate in the synthesis of complex organic molecules. The trifluoromethyl group can influence the electronic properties and reactivity of the molecule, making it useful in medicinal chemistry research and drug discovery.
Chemical Biology Research
Used as a tool compound to probe structure-activity relationships in biological systems. Its incorporation can help researchers understand the impact of fluorination and specific amino acid substitutions on protein function and interactions.
| Molecular weight | 333.30 |
|---|---|
| Empirical formula | C15H18F3NO4 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]20/D +7.3±0.5°, c = 1% in methanol |
| Melting point | 135-138 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Phe(3-CF3)-OH used for?
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Boc-Phe(3-CF3)-OH is primarily used as a building block in peptide synthesis and as an intermediate in chemical synthesis, particularly in the fields of chemical biology and medicinal chemistry research.
What is the CAS number and formula for Boc-Phe(3-CF3)-OH?
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The CAS number is 142995-31-1 and the empirical formula (Hill notation) is C15H18F3NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Phe(3-CF3)-OH with an assay of ≥98.0% (TLC). This product is supplied for research and development purposes and is not intended for pharmaceutical, food, or household use. TSS does not represent it as USP, BP, EP, or other pharmacopoeia grade.
How should Boc-Phe(3-CF3)-OH be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter, such as type N95 (US) or P1 (EN143), may be necessary. Refer to the Safety Data Sheet for detailed handling and hazard information. The compound is classified under WGK 2 (Germany).
How is Boc-Phe(3-CF3)-OH typically shipped by TSS?
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Tech Serve Solutions exports and ships fine chemicals globally. Packaging and shipping methods comply with international regulations for hazardous materials, ensuring safe and secure delivery.
How can I request a quote or sample for Boc-Phe(3-CF3)-OH?
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Please contact our sales team directly via the website or by phone to request a quotation or a sample. Our team will be happy to assist with your specific requirements.
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