Boc-Phe(3,4-F2)-OH
Boc-Phe(3,4-F2)-OH (CAS 198474-90-7) is a protected unnatural amino acid derivative with the molecular formula C14H17F2NO4 and a molecular weight of 301.29 g/mol. This compound is a valuable building block in chemical synthesis and peptide chemistry. It features a tert-butyloxycarbonyl (Boc) protecting group on the amine and two fluorine atoms on the phenyl ring of phenylalanine, enabling precise modifications in complex molecular structures. It is supplied with an assay of ≥98.0% by TLC.
- IUPAC
- Boc-3,4-difluoro-L-phenylalanine
- Synonyms
- Boc-3,4-difluoro-L-phenylalanine
Peptide Synthesis
Boc-Phe(3,4-F2)-OH serves as a key intermediate in the synthesis of modified peptides. The difluorinated phenylalanine moiety can be incorporated to study protein structure-activity relationships or to enhance metabolic stability.
Chemical Synthesis
This compound is utilised as a versatile building block in organic synthesis, particularly for creating novel fluorinated compounds and pharmaceuticals. The Boc protecting group facilitates controlled reactions.
Chemical Biology
It is employed in chemical biology research to introduce fluorinated amino acids into biomolecules, aiding in the study of biological processes and drug discovery.
Medicinal Chemistry
The presence of fluorine atoms can significantly influence the pharmacokinetic and pharmacodynamic properties of drug candidates, making this derivative useful in medicinal chemistry research for developing new therapeutic agents.
| Molecular weight | 301.29 |
|---|---|
| Empirical formula | C14H17F2NO4 |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Phe(3,4-F2)-OH used for?
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Boc-Phe(3,4-F2)-OH is primarily used as a building block in peptide synthesis, chemical synthesis, chemical biology, and medicinal chemistry research, particularly for introducing fluorinated phenylalanine derivatives into complex molecules.
What is the CAS number and formula for Boc-Phe(3,4-F2)-OH?
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The CAS number for Boc-Phe(3,4-F2)-OH is 198474-90-7, and its empirical formula is C14H17F2NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Phe(3,4-F2)-OH with an assay of ≥98.0% as determined by TLC. This is a research-grade chemical and is not represented as USP, BP, or EP grade.
How should Boc-Phe(3,4-F2)-OH be handled?
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Handle Boc-Phe(3,4-F2)-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet for detailed handling and safety information. The compound is classified under WGK 2 in Germany.
Is Boc-Phe(3,4-F2)-OH a controlled substance?
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The provided data does not indicate that Boc-Phe(3,4-F2)-OH is a controlled substance.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions professionally packs, ships, and exports chemicals globally, adhering to all relevant international shipping regulations to ensure safe and compliant delivery.
How can I request a sample or quote for Boc-Phe(3,4-F2)-OH?
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To request a sample or obtain a quote for Boc-Phe(3,4-F2)-OH, please contact the Tech Serve Solutions sales team through the website or by phone.
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