Boc-Phe(2-Cl)-OH
Boc-Phe(2-Cl)-OH (CAS: 114873-02-8) is a protected unnatural amino acid derivative, specifically N-tert-butoxycarbonyl-2-chloro-L-phenylalanine. With a molecular weight of 299.75 g/mol, this compound serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and chemical biology. Its unnatural structure allows for the introduction of modified amino acid residues into peptides, enabling research into novel peptide structures and functions.
- IUPAC
- Boc-2-chloro-L-phenylalanine
- Synonyms
- Boc-2-chloro-L-phenylalanine

Peptide Synthesis
Utilised as a protected unnatural amino acid for incorporation into peptide chains. This allows for the creation of modified peptides with altered biological activity or stability.
Chemical Biology Research
Serves as a building block for synthesising peptides and small molecules in chemical biology, aiding the study of biological processes and drug discovery.
Organic Synthesis
A versatile intermediate in organic synthesis, enabling the construction of complex molecules that require a 2-chloro-phenylalanine moiety.
| Molecular weight | 299.75 |
|---|---|
| Empirical formula | C14H18ClNO4 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]20/D −24.5±1°, c = 1% in ethyl acetate |
| Melting point | 94-100 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Phe(2-Cl)-OH used for?
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Boc-Phe(2-Cl)-OH is used as a protected unnatural amino acid building block in peptide synthesis, chemical biology research, and general organic synthesis.
What is the CAS number and formula for Boc-Phe(2-Cl)-OH?
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The CAS number is 114873-02-8, and the empirical formula is C14H18ClNO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Phe(2-Cl)-OH with an assay of ≥98.0% (TLC). This product is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should Boc-Phe(2-Cl)-OH be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter is recommended if airborne exposure is possible. Refer to the Safety Data Sheet for full guidance.
Is Boc-Phe(2-Cl)-OH a controlled substance?
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The provided data does not indicate that Boc-Phe(2-Cl)-OH is a controlled substance.
How is Boc-Phe(2-Cl)-OH packed and shipped?
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This chemical is available for export and is carefully packed according to international shipping regulations to ensure safe transit.
How can I request a sample or quote for Boc-Phe(2-Cl)-OH?
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Please contact the Tech Serve Solutions sales team via our website or by phone to request a sample or a formal quotation for this product.
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