Fluconazole
Fluconazole (CAS 86386-73-4), a synthetic triazole antifungal agent with the molecular formula C13H12F2N6O and a molecular weight of 306.27 g/mol, is a widely used therapeutic compound. It functions by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes. Available as a powder with an assay of ≥98% (HPLC), it is primarily employed in pharmaceutical research and development for its antifungal properties.
- IUPAC
- 2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol
- Synonyms
- 2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol
Antifungal Agent Research
Fluconazole is investigated for its efficacy against various fungal infections, particularly those caused by Candida species. Its mechanism involves disrupting fungal cell membrane integrity by inhibiting key enzymes in the ergosterol biosynthesis pathway.
Pharmaceutical Intermediate
As a key active pharmaceutical ingredient (API), Fluconazole serves as a crucial intermediate in the synthesis of antifungal medications. Its well-defined chemical structure and properties make it suitable for large-scale pharmaceutical manufacturing.
Drug Discovery and Development
This compound is utilized in drug discovery programs aimed at identifying novel antifungal therapies or understanding resistance mechanisms. Its known pharmacological profile aids in the evaluation of new drug candidates.
| Molecular weight | 306.27 |
|---|---|
| Empirical formula | C13H12F2N6O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Solubility | DMSO: soluble5 mg/mL |
| Storage temperature | room temp |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CYP1A2(1544) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fluconazole used for?
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Fluconazole is primarily used as an antifungal agent in pharmaceutical research and development. It inhibits ergosterol synthesis, crucial for fungal cell membranes, and is investigated for treating various fungal infections.
What is the CAS number and molecular formula for Fluconazole?
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The CAS number for Fluconazole is 86386-73-4, and its molecular formula is C13H12F2N6O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fluconazole with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated in the specifications.
What are the primary safety hazards associated with Fluconazole?
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Fluconazole is classified with GHS07 symbol and a 'Warning' signal word. It carries hazard statements H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment including dust mask (N95), eyeshields, and gloves should be used.
How is Fluconazole packed and shipped by TSS?
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Fluconazole is supplied as a powder and stored at room temperature. TSS ensures careful packaging and adherence to all shipping regulations for global export.
How can I request a quote or sample of Fluconazole?
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To request a quote or sample of Fluconazole, please contact the TSS sales team via our website or by phone, providing your specific requirements and shipping details.
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