Flumethasone pivalate
Flumethasone pivalate (CAS 2002-29-1) is a difluorinated corticosteroid ester with the chemical formula C27H36F2O6 and a molecular weight of 494.57 g/mol. It exhibits potent anti-inflammatory, antipruritic, and vasoconstrictive properties. This compound is primarily utilised in dermatological research to investigate the effects of topical corticosteroids, including adrenocortical suppression, plasma protein binding, and the induction of skin atrophy and telangiectasia.
- IUPAC
- 6α,9-Difluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-(2,2-dimethylpropionate)
Adrenocortical Suppression Studies
Flumethasone pivalate is employed in research settings to induce and study adrenocortical suppression, offering insights into the hypothalamic-pituitary-adrenal axis function.
Plasma Transcortin Binding Research
This corticosteroid ester serves as a valuable tool for researchers investigating the binding dynamics of corticosteroids to plasma transcortin.
Cutaneous Atrophy and Telangiectasia Investigations
Its known effects on skin make flumethasone pivalate useful for experimental models examining the development of cutaneous atrophy and telangiectasia.
| Molecular weight | 494.57 |
|---|---|
| Empirical formula | C27H36F2O6 |
| Application | Flumethasone pivalate is a topical corticosteroid. Prompt decrease in inflammation, exudation and itching is experienced after application. It is a difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. It is used to study adrenocortical suppression1, plasma transcortin binding, and cutaneous atrophy and telangiectasia2. |
Hazard statements
- H351Suspected of causing cancer
Precautionary statements
- P281Use personal protective equipment as required
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 40 |
| Safety statements (S) | 22-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Flumethasone Pivalate used for?
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Flumethasone pivalate is used in research to study adrenocortical suppression, plasma transcortin binding, and cutaneous atrophy and telangiectasia. It is a topical corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties.
What is the CAS number and chemical formula for Flumethasone Pivalate?
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The CAS number for Flumethasone Pivalate is 2002-29-1, and its chemical formula is C27H36F2O6.
What grade and purity does Tech Serve Solutions supply for Flumethasone Pivalate?
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Tech Serve Solutions supplies Flumethasone Pivalate (CAS 2002-29-1) with a purity of ≥98%. This product is supplied for research and development purposes only and is not intended for medicinal, household, or other uses. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations when handling Flumethasone Pivalate?
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Flumethasone Pivalate is classified as harmful if swallowed and suspected of causing cancer (H351). Appropriate personal protective equipment, including eyeshields, gloves, and a type N100 respirator (US) or P3 (EN143) respirator filter, should be used. Handle with caution in a well-ventilated area.
How is Flumethasone Pivalate packed and shipped?
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Flumethasone Pivalate is carefully packed in suitable containers to ensure stability during transit and is exported globally by Tech Serve Solutions.
How can I request a quote or sample for Flumethasone Pivalate?
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To request a quote or a sample of Flumethasone Pivalate, please contact our sales team through the website or by direct inquiry, providing your details and the product CAS number 2002-29-1.
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