1-Z-Piperazine
1-Z-Piperazine (CAS: 31166-44-6), with the molecular formula C12H16N2O2 and a molecular weight of 220.27 g/mol, is a valuable heterocyclic building block. It is primarily utilised in chemical synthesis, particularly for the construction of complex organic molecules. Its applications include the development of novel pharmaceutical intermediates and advanced materials. This compound is supplied by TSS with an assay of 98%.
- IUPAC
- 1-(Benzyloxycarbonyl)piperazine,1-Cbz-Piperazine,Benzyl piperazine-1-carboxylate
- Synonyms
- 1-(Benzyloxycarbonyl)piperazine1-Cbz-PiperazineBenzyl piperazine-1-carboxylate
Synthesis of Triazine-based Macrocycles
1-Z-Piperazine has been employed as a key reagent in the synthesis of triazine-based macrocyclic scaffolds. These structures are of interest in supramolecular chemistry and materials science.
Preparation of Piperazine Derivatives
The compound serves as a precursor for the synthesis of mono-piperazine substituted compounds. These derivatives can be further functionalised for various chemical applications.
Chemical Synthesis Intermediate
As a versatile building block, 1-Z-Piperazine facilitates complex organic syntheses. It is employed in the development of novel chemical entities for research and industrial purposes.
| Molecular weight | 220.27 |
|---|---|
| Empirical formula | C12H16N2O2 |
| Assay | 98% |
| Boiling point | 158-161 °C/1.4 mmHg(lit.) |
| Density | 1.142 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.546(lit.) |
| Application | 1-Z-Piperazine was used in the synthesis of triazine-based macrocyclic scaffolds1 and mono-piperazine compounds2 . |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Z-Piperazine used for?
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1-Z-Piperazine is used as a building block in chemical synthesis, including the preparation of triazine-based macrocyclic scaffolds and mono-piperazine compounds.
What are the CAS number and formula for 1-Z-Piperazine?
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The CAS number for 1-Z-Piperazine is 31166-44-6, and its molecular formula is C12H16N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Z-Piperazine with an assay of 98%. TSS does not represent this product as USP, BP, or EP grade.
How should 1-Z-Piperazine be handled safely?
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1-Z-Piperazine is a Warning substance (GHS07) and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields and gloves, should be worn. Work in a well-ventilated area or use a suitable respirator.
How is 1-Z-Piperazine exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 1-Z-Piperazine, adhering to all relevant shipping regulations.
How can I request a sample or quote for 1-Z-Piperazine?
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To request a sample or quote for 1-Z-Piperazine, please contact the Tech Serve Solutions sales team through our website or by phone.
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