1-Z-3-Pyrrolidinone
1-Z-3-Pyrrolidinone (CAS: 130312-02-6; Formula: C12H13NO3; Mol. Wt.: 219.24) is a versatile heterocyclic building block used in chemical synthesis. This compound, featuring a pyrrolidinone core with a benzyloxycarbonyl protecting group, serves as a key intermediate in the development of complex organic molecules. Its utility spans research laboratories and industrial chemical production, contributing to the synthesis of novel compounds and pharmaceutical intermediates.
- IUPAC
- 1-Carbobenzyloxy-3-pyrrolidinone,1-Cbz-3-pyrrolidinone,3-Oxo-1-pyrrolidinecarboxylic acid, phenylmethyl ester,3-Oxopyrrolidine-1-carboxylic acid benzyl ester,N-Benzyloxycarbonyl-3-pyrrolidinone
- Synonyms
- 1-Carbobenzyloxy-3-pyrrolidinone1-Cbz-3-pyrrolidinone3-Oxo-1-pyrrolidinecarboxylic acid, phenylmethyl ester3-Oxopyrrolidine-1-carboxylic acid benzyl esterN-Benzyloxycarbonyl-3-pyrrolidinone
Organic Synthesis Intermediate
1-Z-3-Pyrrolidinone acts as a valuable intermediate in various organic synthesis pathways. Its protected pyrrolidinone structure allows for selective functionalization in multi-step synthetic procedures.
Pharmaceutical Research
This compound is employed in the synthesis of potential pharmaceutical agents and drug discovery programs. Its chiral nature and functional groups make it a useful scaffold for medicinal chemistry efforts.
Development of Heterocyclic Compounds
As a heterocyclic building block, 1-Z-3-Pyrrolidinone is instrumental in constructing diverse heterocyclic ring systems critical for various chemical applications.
| Molecular weight | 219.24 |
|---|---|
| Empirical formula | C12H13NO3 |
| Assay | 96% |
| Density | 1.1897 g/mL at 25 °C |
| Refractive index | n20/D 1.5410 |
| Impurities tested | 4% DCM detected in first lot(4% DCM) |
Hazard statements
- H351Suspected of causing cancer
Precautionary statements
- P281Use personal protective equipment as required
| Flash point | >110 °C / >230 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 40 |
| Safety statements (S) | 23-24/25-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Z-3-Pyrrolidinone used for?
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1-Z-3-Pyrrolidinone is primarily used as an intermediate in organic synthesis and in pharmaceutical research for the development of new chemical entities and heterocyclic compounds.
What are the CAS number and formula for 1-Z-3-Pyrrolidinone?
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The CAS number is 130312-02-6, and the empirical formula is C12H13NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Z-3-Pyrrolidinone with an assay of 96%. This is a technical/research grade material, and TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
How should 1-Z-3-Pyrrolidinone be handled safely?
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1-Z-3-Pyrrolidinone is classified as suspected of causing cancer (H351). Handle with appropriate personal protective equipment in a well-ventilated area, avoiding exposure. Refer to the Safety Data Sheet (SDS) for detailed handling instructions.
Is 1-Z-3-Pyrrolidinone available for export?
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Yes, Tech Serve Solutions, established in 1998, is a specialist global supplier and exporter of fine chemicals, including 1-Z-3-Pyrrolidinone.
How can I request a sample or quote for 1-Z-3-Pyrrolidinone?
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To request a sample or quote, please use the contact form on our website or reach out to our sales department with your specific requirements.
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