3-(Dimethylamino)propionitrile
3-(Dimethylamino)propionitrile (CAS: 1738-25-6) is a clear liquid with the linear formula (CH3)2NCH2CH2CN and a molecular weight of 98.15 g/mol. This organic building block is primarily used as a catalyst in polymerisation reactions, similar to TEMED, for forming oxygen-free radicals from ammonium persulfate. It is an essential reagent in the preparation of polyacrylamide gels for electrophoresis and various chemical synthesis applications.
- IUPAC
- DMAPN
- Synonyms
- DMAPN
Polymerisation Catalyst
Acts as a catalyst, analogous to TEMED, in initiating polymerisation reactions. It facilitates the formation of free radicals from ammonium persulfate, which then drive the polymerisation of acrylamide and bis-acrylamide monomers.
Electrophoresis Gel Preparation
Essential for the cross-linking of polyacrylamide gels used in electrophoresis. Its role in initiating polymerisation is critical for creating the gel matrix required for molecular separation.
Chemical Synthesis
Utilised as a versatile building block in organic synthesis. Its nitrile and amine functionalities allow for diverse chemical transformations, contributing to the creation of more complex molecules.
Laboratory Reagent
A key reagent in molecular biology and biochemistry laboratories. Its applications extend to protein sequencing and structural analysis, where precise gel formation is paramount.
| Molecular weight | 98.15 |
|---|---|
| Linear formula | (CH3)2NCH2CH2CN |
| Assay | ≥99.5% (GC) |
| Grade | for electrophoresis |
| Boiling point | 171 °C/750 mmHg(lit.) |
| Density | 0.87 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.426(lit.)n20/D 1.426 |
| Melting point | −43 °C(lit.) |
| Impurities tested | ≤0.2% water |
| Application | Catalyst similar to TEMED used to form oxygen free radicals from ammonium persulfate. Free radicals cause acrylamide and bis-acrylamide to polymerize. |
| Suitability | in accordance for electrophoresis test |
Hazard statements
- H302Harmful if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 63 °C / 145.4 °F |
| Transport (UN / ADR) | UN 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 21-36 |
| Safety statements (S) | 26-36/37 |
| Cation traces | Ca: ≤10 mg/kgCd: ≤5 mg/kgCo: ≤5 mg/kgCr: ≤5 mg/kgCu: ≤5 mg/kgFe: ≤5 mg/kgK: ≤50 mg/kgMg: ≤5 mg/kgMn: ≤5 mg/kgNa: ≤50 mg/kgNi: ≤5 mg/kgPb: ≤5 mg/kgZn: ≤5 mg/kg |
| Anion traces | chloride (Cl-): ≤50 mg/kgsulfate (SO42-): ≤50 mg/kg |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Dimethylamino)propionitrile used for?
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3-(Dimethylamino)propionitrile (CAS: 1738-25-6) is primarily used as a catalyst in the polymerisation of acrylamide and bis-acrylamide for electrophoresis gels, and as a building block in chemical synthesis.
What is the CAS number and formula for 3-(Dimethylamino)propionitrile?
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The CAS number for 3-(Dimethylamino)propionitrile is 1738-25-6 and its linear formula is (CH3)2NCH2CH2CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-(Dimethylamino)propionitrile with an assay of ≥99.5% (GC) and a grade suitable for electrophoresis, with ≤0.2% water impurities. We do not represent this product as USP, BP, or EP grade.
What are the safety precautions for handling 3-(Dimethylamino)propionitrile?
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3-(Dimethylamino)propionitrile is classified with the GHS07 symbol and a Warning signal word. It carries hazard statements H302 + H312 (Harmful if swallowed or in contact with skin) and H319 (Causes serious eye irritation). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, should be used. Refer to the Safety Data Sheet for full details.
How is 3-(Dimethylamino)propionitrile packed, shipped, and exported?
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Tech Serve Solutions can pack, ship, and export 3-(Dimethylamino)propionitrile globally, adhering to all relevant regulations for hazardous materials such as UN 1993 / PGIII.
How can I request a sample or quote for 3-(Dimethylamino)propionitrile?
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To request a sample or a quote for 3-(Dimethylamino)propionitrile, please contact our sales department through the website or by phone. Our team will be pleased to assist you.
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