Flunixin meglumine
Flunixin meglumine (CAS 42461-84-7) is a non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its empirical formula is C14H11F3N2O2·C7H17NO5 and it has a molecular weight of 491.46 g/mol. Flunixin meglumine is primarily utilised in veterinary medicine for its efficacy in managing pain and inflammation associated with conditions such as colic and endotoxemia in horses.
- IUPAC
- 2-[[2-Methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid meglumine salt,Banamine
- Synonyms
- 2-[[2-Methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid meglumine salt,Banamine
Veterinary Pain Management
Flunixin meglumine is widely used in veterinary practice to alleviate pain and inflammation in animals. It is particularly effective in treating conditions like equine colic, where its rapid action can provide significant relief.
Anti-inflammatory Agent
This compound acts as a potent inhibitor of cyclooxygenase (COX) enzymes, thereby reducing the production of prostaglandins, key mediators of inflammation. This makes it valuable for managing inflammatory responses in various animal species.
Treatment of Endotoxemia
In horses, flunixin meglumine is employed to manage the clinical signs associated with endotoxemia, a serious condition often triggered by bacterial infections. It helps to mitigate the inflammatory cascade and associated symptoms.
| Molecular weight | 491.46 |
|---|---|
| Empirical formula | C14H11F3N2O2·C7H17NO5 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | H2O: freely soluble |
| Application | Flunixin meglumine (IC50 = 1 nM) can be used as a drug for animals for the management of intestinal ischaemia, colic, and endotoxemia in horses. |
| Melting point | 136.6-137.4 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Flunixin meglumine used for?
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Flunixin meglumine is used in veterinary medicine for the management of intestinal ischaemia, colic, and endotoxemia in horses, and generally as an anti-inflammatory and analgesic agent.
What is the CAS number and formula for Flunixin meglumine?
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The CAS number is 42461-84-7 and the empirical formula (Hill notation) is C14H11F3N2O2·C7H17NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Flunixin meglumine with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should Flunixin meglumine be handled?
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Handle Flunixin meglumine with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, to avoid skin and eye irritation and respiratory tract irritation.
How is Flunixin meglumine packed and shipped?
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Flunixin meglumine is available as a white to beige powder. It is typically packed securely for transport and exported globally by Tech Serve Solutions.
How can I request a sample or quote for Flunixin meglumine?
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To request a sample or obtain a quote for Flunixin meglumine, please contact our sales team through the website or by phone.
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