Triethylsilyl trifluoromethanesulfonate
Triethylsilyl trifluoromethanesulfonate (CAS 79271-56-0) is a silicon-based chemical with the formula CF3SO3Si(C2H5)3 and a molecular weight of 264.34 g/mol. As a potent triethylsilylating agent, it is widely employed in organic synthesis. Its primary application lies in the protection and derivatization of various functional groups, facilitating complex chemical transformations. This reagent is indispensable for researchers and industrial chemists requiring precise control over synthetic pathways.
- IUPAC
- TES triflate,Trifluoromethanesulfonic acid triethylsilylester
- Synonyms
- TES triflateTrifluoromethanesulfonic acid triethylsilylester
Triethylsilylation Agent
This compound serves as a highly effective triethylsilylating agent in organic synthesis. It facilitates the introduction of the triethylsilyl (TES) group onto various substrates, commonly used for protecting hydroxyl, amine, and thiol functionalities during multi-step reactions.
Protecting Group Chemistry
In complex syntheses, the TES group offers robust protection for sensitive functional groups. Triethylsilyl trifluoromethanesulfonate allows for efficient and selective silylation, enabling chemists to perform other transformations without unwanted side reactions involving the protected moiety.
Derivatization Reagent
It can be used for the derivatization of analytes, particularly in analytical chemistry for improving volatility or chromatographic separation. The resulting silylated derivatives are often more amenable to detection by mass spectrometry or gas chromatography.
| Molecular weight | 264.34 |
|---|---|
| Linear formula | CF3SO3Si(C2H5)3 |
| Assay | 99% |
| Boiling point | 85-86 °C/12 mmHg(lit.) |
| Density | 1.169 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.389(lit.) |
| Application | Triethylsilylating agent.1,2 |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 66 °C / 150.8 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Triethylsilyl trifluoromethanesulfonate used for?
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Triethylsilyl trifluoromethanesulfonate is primarily used as a triethylsilylating agent in organic synthesis, particularly for protecting functional groups like hydroxyl and amine groups, and for derivatization purposes.
What is the CAS number and formula for Triethylsilyl trifluoromethanesulfonate?
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The CAS number is 79271-56-0 and the chemical formula is CF3SO3Si(C2H5)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Triethylsilyl trifluoromethanesulfonate with an assay of 99%. This product is supplied for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should Triethylsilyl trifluoromethanesulfonate be handled safely?
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Triethylsilyl trifluoromethanesulfonate is a corrosive substance (H314). Handle with extreme care, wearing appropriate personal protective equipment including a face shield, gloves, goggles, and a suitable respirator. Ensure adequate ventilation and follow emergency procedures in case of contact or exposure.
How is this chemical packed, shipped, and exported?
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This chemical is packed in accordance with international shipping regulations for hazardous materials (UN 3265, Class 8, PG II). Tech Serve Solutions has extensive experience in exporting chemicals globally.
How can I request a sample or quote for Triethylsilyl trifluoromethanesulfonate?
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To request a sample or a detailed quote, please contact our sales department through the website or by phone, referencing the product name and CAS number 79271-56-0.
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