Boc-Phe(3-CN)-OH
Boc-Phe(3-CN)-OH, identified by CAS number 131980-30-8 and molecular formula C15H18N2O4, is a protected unnatural amino acid derivative. With a molecular weight of 290.31 g/mol, it serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and chemical biology research. Its structure features a cyano-substituted phenylalanine core with an N-terminal Boc protecting group, enabling controlled peptide chain elongation and the introduction of unique functionalities.
- IUPAC
- Boc-3-cyano-L-phenylalanine
- Synonyms
- Boc-3-cyano-L-phenylalanine

Peptide Synthesis
Utilised as a non-canonical amino acid building block in solid-phase or solution-phase peptide synthesis to create modified peptides with altered biological properties or enhanced stability.
Chemical Biology Research
Incorporated into peptide probes or peptidomimetics for studying protein-ligand interactions, enzyme mechanisms, or as components in drug discovery programs.
Organic Synthesis Intermediate
Serves as a versatile intermediate for the synthesis of complex organic molecules, leveraging the reactivity of the protected amino acid and the cyano group.
| Molecular weight | 290.31 |
|---|---|
| Empirical formula | C15H18N2O4 |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Phe(3-CN)-OH primarily used for?
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Boc-Phe(3-CN)-OH is primarily used as a building block in peptide synthesis and as an intermediate in chemical biology and organic synthesis research.
What are the CAS number and molecular formula for Boc-Phe(3-CN)-OH?
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The CAS number is 131980-30-8 and the molecular formula is C15H18N2O4.
What grade and purity does Tech Serve Solutions supply for Boc-Phe(3-CN)-OH?
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Tech Serve Solutions supplies Boc-Phe(3-CN)-OH with an assay of ≥98.0% as determined by TLC. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should Boc-Phe(3-CN)-OH be handled safely?
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Safe handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. The substance has a WGK Germany rating of 3, indicating a high hazard to water.
How is Boc-Phe(3-CN)-OH typically packed and exported?
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Boc-Phe(3-CN)-OH is packed securely for transport and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for Boc-Phe(3-CN)-OH?
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To request a sample or quote, please use the contact form on our website or contact our sales department directly.
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