Boc-Phe(3-F)-OH
Boc-Phe(3-F)-OH (CAS: 114873-01-7), a fluorinated derivative of phenylalanine, presents as a key building block in advanced chemical synthesis. With the molecular formula C14H18FNO4 and a molecular weight of 283.30 g/mol, this compound is essential for introducing modified phenylalanine residues into peptides. Its applications span chemical biology and peptide chemistry, facilitating the creation of novel biomolecules and research probes.
- IUPAC
- Boc-3-fluoro-L-phenylalanine
Peptide Synthesis
Utilised as an unnatural amino acid building block in solid-phase or solution-phase peptide synthesis to create modified peptide sequences with altered pharmacological or biochemical properties.
Medicinal Chemistry
Incorporated into drug discovery programs for the development of novel therapeutic agents, where the fluorine atom can modulate metabolic stability, binding affinity, and lipophilicity.
Chemical Biology Research
Serves as a valuable tool for probing protein structure-function relationships and developing new chemical probes for biological systems.
| Molecular weight | 283.30 |
|---|---|
| Empirical formula | C14H18FNO4 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]20/D +6.5±1°, c = 1% in methanol |
| Melting point | 75-80 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Phe(3-F)-OH used for?
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Boc-Phe(3-F)-OH is primarily used as an unnatural amino acid building block in peptide synthesis, medicinal chemistry, and chemical biology research to create modified peptides and explore structure-activity relationships.
What is the CAS number and molecular formula for Boc-Phe(3-F)-OH?
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The CAS number is 114873-01-7 and the molecular formula is C14H18FNO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Phe(3-F)-OH with a purity of ≥98.0% (TLC). This product is a research/technical grade material and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should Boc-Phe(3-F)-OH be handled?
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Handle Boc-Phe(3-F)-OH with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and consider using a P1 (EN143) or N95 (US) respirator filter if dust is generated. It has a melting point of 75-80 °C.
How is Boc-Phe(3-F)-OH shipped?
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Boc-Phe(3-F)-OH is carefully packaged and exported by Tech Serve Solutions, adhering to all necessary regulations for chemical shipments.
How can I request a sample or quote for Boc-Phe(3-F)-OH?
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To request a sample or a quote for Boc-Phe(3-F)-OH, please contact our sales team through the website or by phone.
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