Boc-Phe(4-CF3)-OH
Boc-Phe(4-CF3)-OH (CAS: 114873-07-3) is a valuable unnatural amino acid derivative with the molecular formula C15H18F3NO4 and a molecular weight of 333.30 g/mol. This compound serves as a crucial building block in chemical synthesis, particularly within peptide chemistry and chemical biology research. Its trifluoromethyl substitution offers unique properties for developing novel peptides and biochemical probes.
- IUPAC
- Boc-4-(trifluoromethyl)-L-phenylalanine
- Synonyms
- Boc-4-(trifluoromethyl)-L-phenylalanine
Peptide Synthesis
Utilised as a protected unnatural amino acid for incorporation into peptide sequences, enabling the study of structure-activity relationships and the development of modified peptides with enhanced properties.
Chemical Biology Research
Serves as a versatile reagent for creating modified peptides or small molecules used to probe biological pathways and protein functions, leveraging the effects of the trifluoromethyl group.
Drug Discovery and Development
Acts as a key intermediate in the synthesis of potential pharmaceutical candidates, where the trifluoromethyl-phenylalanine moiety can influence pharmacokinetic and pharmacodynamic profiles.
Organic Synthesis
Employed as a chiral building block in the construction of complex organic molecules where specific stereochemistry and functionality are required.
| Molecular weight | 333.30 |
|---|---|
| Empirical formula | C15H18F3NO4 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]20/D +5.4±0.7°, c = 1% in methanol |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Phe(4-CF3)-OH used for?
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Boc-Phe(4-CF3)-OH is primarily used in peptide synthesis, chemical biology research, and drug discovery as a protected unnatural amino acid building block.
What are the CAS number and formula for Boc-Phe(4-CF3)-OH?
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The CAS number is 114873-07-3 and the empirical formula is C15H18F3NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Phe(4-CF3)-OH with an assay of ≥98.0% (TLC). This product is supplied for research and development use and is not represented as USP, BP, EP, or other pharmacopoeial grades.
What are the safety considerations when handling Boc-Phe(4-CF3)-OH?
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When handling Boc-Phe(4-CF3)-OH, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. The compound has a WGK (Germany) rating of 3, indicating it is hazardous to water.
How is Boc-Phe(4-CF3)-OH packed and shipped?
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Boc-Phe(4-CF3)-OH is carefully packed according to industry best practices for chemical handling and is available for global export.
How can I request a sample or quote for Boc-Phe(4-CF3)-OH?
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To request a sample or a quote for Boc-Phe(4-CF3)-OH, please contact our sales team through the website or by phone.
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