Boc-Phe(4-Cl)-OH
Boc-Phe(4-Cl)-OH (CAS 68090-88-0) is a protected unnatural amino acid derivative, N-Boc-4-chloro-L-phenylalanine, with a molecular weight of 299.75 g/mol. This compound is a valuable building block in chemical synthesis and peptide chemistry. Its structure incorporates a chlorophenylalanine moiety, making it useful for introducing specific structural modifications into peptides and other organic molecules for research and development purposes.
- IUPAC
- Boc-4-chloro-L-phenylalanine
- Synonyms
- Boc-4-chloro-L-phenylalanine

Peptide Synthesis
Utilised as a protected unnatural amino acid in solid-phase or solution-phase peptide synthesis to create modified peptides with altered pharmacological or structural properties.
Medicinal Chemistry Research
Serves as a key intermediate for the synthesis of novel drug candidates, particularly where a chlorinated phenylalanine residue is desired for target binding or metabolic stability.
Chemical Biology Probes
Incorporated into peptides or small molecules to generate probes for studying biological systems, protein-ligand interactions, or enzymatic activity.
Organic Synthesis Building Block
Employed as a chiral building block in complex organic synthesis pathways for creating diverse chemical entities and fine chemicals.
| Molecular weight | 299.75 |
|---|---|
| Empirical formula | C14H18ClNO4 |
| Assay | ≥96.0% (TLC) |
| Optical activity | [α]20/D +26±3°, c = 1% in ethyl acetate |
| Melting point | ~110 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Phe(4-Cl)-OH used for?
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Boc-Phe(4-Cl)-OH is primarily used as a protected unnatural amino acid derivative in peptide synthesis and as a building block in medicinal chemistry and organic synthesis research.
What is the CAS number and formula for Boc-Phe(4-Cl)-OH?
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The CAS number is 68090-88-0, and the empirical formula is C14H18ClNO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Phe(4-Cl)-OH with an assay of ≥96.0% (TLC). TSS does not represent this product as USP, BP, or EP grade.
How should Boc-Phe(4-Cl)-OH be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use a suitable respirator filter (type N95 or P1) if airborne exposure is possible.
Is Boc-Phe(4-Cl)-OH a controlled substance?
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The provided data does not indicate that Boc-Phe(4-Cl)-OH is a controlled substance.
How is this chemical packed and exported?
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Tech Serve Solutions securely packs and exports chemicals globally, adhering to all necessary regulations for safe transit.
How can I request a sample or quote for Boc-Phe(4-Cl)-OH?
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Please contact our sales team via the website or by phone to request a sample or a detailed quotation for Boc-Phe(4-Cl)-OH.
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