Boc-Phe(4-NH2)-OH
Boc-Phe(4-NH2)-OH (CAS: 55533-24-9), with the molecular formula C14H20N2O4 and a molecular weight of 280.32 g/mol, is a protected unnatural amino acid derivative. It plays a crucial role in chemical synthesis and peptide chemistry, particularly in the development of novel peptides and peptidomimetics. Its structure allows for specific modifications and incorporation into complex molecular designs for various research applications.
- IUPAC
- Boc-4-amino-L-phenylalanine
- Synonyms
- Boc-4-amino-L-phenylalanine
Peptide Synthesis
Boc-Phe(4-NH2)-OH serves as a protected building block in solid-phase or solution-phase peptide synthesis. The Boc protecting group facilitates controlled peptide chain elongation, while the 4-amino substituent allows for post-synthetic modifications or conjugation.
Chemical Biology Research
This compound is valuable in chemical biology for constructing modified peptides and probes. The amino group offers a handle for labelling, cross-linking, or immobilisation, aiding in the study of biological processes and protein interactions.
Drug Discovery and Development
As an unnatural amino acid derivative, Boc-Phe(4-NH2)-OH can be incorporated into peptidomimetics or small molecules to enhance pharmacological properties, such as stability, bioavailability, or receptor binding affinity.
Organic Synthesis Intermediate
Beyond peptide chemistry, it functions as an intermediate in complex organic syntheses requiring a phenylalanine scaffold with a protected amine and a functionalizable aromatic ring.
| Molecular weight | 280.32 |
|---|---|
| Empirical formula | C14H20N2O4 |
| Assay | ≥98.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Phe(4-NH2)-OH used for?
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Boc-Phe(4-NH2)-OH is primarily used in peptide synthesis, chemical biology research, and drug discovery as a protected unnatural amino acid building block.
What are the CAS number and molecular formula for Boc-Phe(4-NH2)-OH?
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The CAS number for Boc-Phe(4-NH2)-OH is 55533-24-9, and its molecular formula is C14H20N2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Phe(4-NH2)-OH with a minimum purity of ≥98.0% (HPLC), as determined by assay. We do not represent this product as USP, BP, or EP grade.
How should Boc-Phe(4-NH2)-OH be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. In environments with potential for aerosol exposure, a type N95 (US) or type P1 (EN143) respirator filter should be used. The substance is classified under WGK 2 in Germany.
How is Boc-Phe(4-NH2)-OH packed and shipped?
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TSS offers Boc-Phe(4-NH2)-OH in various quantities suitable for laboratory and research needs, and it is exported globally adhering to all relevant shipping regulations.
How can I request a sample or quote for Boc-Phe(4-NH2)-OH?
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To request a sample or obtain a quote for Boc-Phe(4-NH2)-OH, please contact our sales department via the website or by phone.
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